Diligence memo · auto-generated · as of July 2, 2026

VYNE Therapeutics Inc.

VYNE Therapeutics Inc. looks over-valued against its niche peers and is at-risk on financing cadence.

WatchOverdue for a raise versus sector cadence — could be a bridge, a down round, or distress. Watch for the next filing.

Businessfiled

VYNE Therapeutics Inc. operates in Pharmaceuticals, based in BRIDGEWATER.

Sub-sector tags: pharma.

No verified homepage on file yet — operating evidence is limited to the public record.

Capital & rounds (filed)filed

VYNE Therapeutics Inc. has raised $139M in disclosed capital across 4 recorded rounds, aggregated from public filings. Its latest round is modeled as Series C (a $40M–$100M round).

Largest single filing: $88M on 2023-11-01.

Most recent recorded round closed around 2023-11-01.

Valuation (modeled)modeled

Provath models VYNE Therapeutics Inc. at approximately $972M (range $286M–$1.6B). This is an algorithmic estimate from round sizes and same-niche peers — not a quoted or reported figure.

Read: Over-valued. Modeled value is 1.69× the median modeled value of Series C Pharmaceuticals companies in 2022–2024 (30 peers) — value vs value, same stage and era.

Financing rhythm & timingmixed

Historic cadence: a new round about every 43 months.

Last raise 2.7 yr ago; this sector typically re-raises about every 13 months.

Past due for a raise versus sector cadence — watch for distress or a bridge.

The last round stepped up 293.8× from the prior — scaling.

Comparablesmixed

Capital scale ranks ahead of 94% of Pharmaceuticals peers (1613 compared).

Modeled value ranks above 88% of those peers.

Closest niche peers: Vigil Neuroscience, Inc., Leap Therapeutics, Inc., Alimera Sciences Inc, Lusaris Therapeutics, Inc., Context Therapeutics Inc..

Peoplefiled

20 named people on file across officers, directors and signatories.

Risks & flagsmixed

Overdue for a raise versus sector norm — distress or bridge risk.

Modeled above niche peers — valuation risk on entry.

No clearly named CEO/founder/principal in the surfaced records — key-person evidence is thin.