Companies · Pharmaceuticals

Isis Pharmaceuticals Inc

CARLSBAD · Pharmaceuticals

Diligence memoA one-page analyst read on Isis Pharmaceuticals Inc — recommendation, valuation, rhythm, risks.
$201.3M
Total raised · real
1
Rounds
Latest step-up
Top 5%
Sector rank · raised
Series D+
Latest stage · inferred · Mon Aug 13 2012 00:00:00 GMT+0000 (Coordinated Universal Time)

Isis Pharmaceuticals Inc has raised $201M over 1 round; too few niche peers to rank its valuation yet.

Synthesized from the figures below est. — every claim rests on a number shown on this page. Valuation uses the pharma sector profile.

Analyst read est. — computed against this company's niche peers in the same era. Inputs shown; not a quoted figure.

Dormant
  • Last raise 13.9 yr ago; this sector typically re-raises about every 13 months.
  • Only one round on record and long silent — often defunct, acquired, or gone quiet.
Leadership

No named principal in this company's public records yet — see all operators below.

Explore how these operators interlock with other companies in the operator network.

Where it sits in Pharmaceuticals

Isis Pharmaceuticals Inc is one of 1613 Pharmaceuticals companies tracked from CARLSBAD. By capital raised it ranks among the largest (ahead of 96% of sector peers), and among the largest by modeled valuation est..

Ranking is computed against this company's own sector cohort — reported capital is fact; valuation tiers are modeled.

As reported in public records reported — not modeled.

US
Jurisdiction
Amount raised vs valuation, by round

Solid bars are reported offering amounts reported; hatched bars are the modeled post-money valuation est. — both on one shared scale so you can read raise-vs-worth at each round directly. Use the toggles to overlay data labels and the niche-peer / market average value lines.

Amount raised · realModeled valuation · estCumulative funded · real
$0$2.5B$5.0B$7.5B$10.0BSeries D+ · 2012-08-13 Raised $201M (real) Modeled valuation $7.1B (est)$201M$7.1BSeries D+2012

The line shows cumulative reported funding over the period; + labels show new capital added between points when there is room. Toggle on-bar figures, plus the niche-peer and market averages, to read this company against its cohort. Benchmarks are modeled medians.

Financing ladder & sequence gaps
Series D+$201.3M · 2012

Stages are modeled from round size (public records carry no series label). No record for: Pre-Seed, Seed, Series A, Series B, Series C — the company may have raised it under a different exemption, merged it into an adjacent record, or skipped it. Sequence completeness: 17%.

Modeled valuation trajectory
$7.1B
Base estimate est.
$958.0M
Conservative case
$15.6B
Upside case
$1.7B
Modeled post-money

Round size and date are reported; the stage label is inferred from round size (latest is Series D+a $100M–$400M round). Valuation is modeled from stage benchmarks scaled by the pharma sector profile. Directional, not a quoted figure.

Not enough modeled valuation points to chart a trajectory.

Model inputs · modeled:benchmark-stage-stepup-v1
12%
Dilution assumption
Implied ownership sold in the financing.
71%
Survival probability
57% low · 79% high
1.35×/yr
Annual markup
1.51×/yr upside case
6.0 yr
Elapsed time used
13.9 yr actual, capped for stale marks
pharma
Sector profile
Adjusts growth and survival by industry.
Financing rhythm
Avg between rounds
Capital velocity
13.9 yr
On record since
2012
First round
1
Rounds on file
How it compares to the market

Benchmarked against 1613 companies in Pharmaceuticals. Each bar is a median (the middle company, not an average — outliers don't skew it). Two yardsticks: real money raised (reported on Form D) and modeled value (our estimate est.). These are whole-sector medians across all stages, except the per-stage row.

Total raised — vs sector median (real $, all stages) 25× above median
This company$201.3M
Sector median$8.1M
Latest round — vs other Series D+ rounds in sector (real $, this stage) 1.8× above median
This company$201.3M
Sector median$111.8M
Modeled value — vs sector median (estimate, all stages) 93× above median
This company$7.1B
Sector median$76.1M

Raised more than 96% of sector peers (real $). Modeled value above 99% of peers (estimate).

Niche peers — same stage & era

A tighter cohort than the sector chart above — only companies at the same stage (Series D+) that last raised in the same ~3-year era, ranked by modeled value est. (not money raised). This is the exact set the analyst read compares against, so a like-for-like cohort is what makes "over/under-valued" meaningful.

Not enough valued peers in this cohort to chart positioning.

CompanyStageRaised · realValue · estvs peer med.
Isis Pharmaceuticals Inc this companySeries D+$201.3M$7.1B1.23×
Radius Health, Inc.Series D+$191.2M$4.5B0.77×
Full financing history

Stage is inferred from round size est., not reported on the filing — a round's dollar size maps to a bucket: Pre-Seed <$1.0M · Seed $1.0M–$4.0M · Series A $4.0M–$15M · Series B $15M–$40M · Series C $40M–$100M · Series D+ $100M–$400M · Growth/Late >$400M.

StageAmount · realAnnouncedPost-money · estValue · estConf.
Series D+$201.3M2012-08-13$1.7B$7.1B90%
What happened at each round

Step-up, pace versus the sector's normal cadence, and revenue/exemption moves — read straight from the reported round facts reported.

  1. Series D+$201.3M2012-08-13
    • First recorded raise — entered as Series D+.
Intelligence
Modeled next raise
$322.0M
Modeled next size est.range $209.3M$515.2M
Last step-up
Capital velocity

Predictive signals are modeled est. from this company's own cadence and step-up, plus sector benchmarks — directional, not advice. Peer set and a CSV export live in your analyst workspace.

Key people & operators

Officers, directors and promoters named in this company's public recordsreported — the people who run it (not its investors). "Also runs" counts come from name-matching across all records, so verify before acting.

PersonRoleAlso runsTied since
B. Lynne Parshall2 other2012-08
STANLEY T CROOKE1 other2012-08
BRETT P MONIA2012-08
C FRANK BENNETT2012-08
FREDERICK T MUTO2012-08
JOHN C REED2012-08
JOSEPH H WENDER2012-08
JOSEPH R KLEIN III2012-08
RICHARD S GEARY2012-08
SPENCER R BERTHELSEN2012-08
Registry & provenance

Isis Pharmaceuticals Inc is an official record sourced from the U.S. Securities and Exchange Commission (SEC). U.S. data is aggregated from SEC Form D filings.

United States
Country of record
US
Jurisdiction
874015
SEC CIK
Similar companies

Nearest neighbours across the whole database — matched on sector, stage and capital scale, and on shared operators (officers or directors named at both companies in public filings). A discovery shortlist, not a valuation cohort — verify before acting, the same way modeled figures are directional.

CompanySectorStageRaised · realValue · estWhy similar
Akcea Therapeutics, Inc.PharmaceuticalsGrowth/Late$543.2M$19.7Bnetwork2 shared operators · same sector
Regulus Therapeutics Inc.PharmaceuticalsSeries B$170.5M$673.2Mnetwork1 shared operator · same sector
Revolution Medicines, Inc.PharmaceuticalsSeries D+$204.2M$3.5Bsame sector · same stage
Karyopharm Therapeutics Inc.PharmaceuticalsSeries D+$205.2M$2.8Bsame sector · same stage
Opko Health, Inc.PharmaceuticalsSeries D+$206.0M$6.2Bsame sector · same stage
Ardelyx, Inc.PharmaceuticalsSeries D+$210.4M$3.9Bsame sector · same stage
Radius Health, Inc.PharmaceuticalsSeries D+$191.2M$4.5Bsame sector · same stage
MAPS Public Benefit CorpPharmaceuticalsSeries D+$215.1M$2.9Bsame sector · same stage
Frequently asked
How much funding has Isis Pharmaceuticals Inc raised?
Isis Pharmaceuticals Inc has raised approximately $201.3M in disclosed capital across 1 recorded financing round, aggregated from public filings.
What is Isis Pharmaceuticals Inc's estimated valuation?
Provath's modeled valuation for Isis Pharmaceuticals Inc is approximately $7.1B (modeled range $958.0M–$15.6B). This is an algorithmic estimate derived from round sizes and same-niche peers — not a quoted or reported figure.
What funding stage is Isis Pharmaceuticals Inc at?
Isis Pharmaceuticals Inc's latest modeled financing stage is Series D+. Its most recent recorded round closed around Mon Aug 13.
What does Isis Pharmaceuticals Inc do and where is it based?
Isis Pharmaceuticals Inc operates in the Pharmaceuticals sector, based in CARLSBAD.
Explore related

See where Isis Pharmaceuticals Inc sits in the wider market — its sector, location and stage cohorts, each with their own leaderboards and capital-flow timelines.

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