Companies · Pharma

Pyxis Oncology, Inc.

Cambridge · Pharma · refined from filed group “Other Health Care

Diligence memoA one-page analyst read on Pyxis Oncology, Inc. — recommendation, valuation, rhythm, risks.
$194.5M
Total raised · real
2
Rounds
7.8×
Latest step-up
Top 5%
Sector rank · raised
Series D+
Latest stage · inferred · Fri Mar 05 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

Pyxis Oncology, Inc. looks fair against its niche peers and is dormant on financing cadence.

Synthesized from the figures below est. — every claim rests on a number shown on this page. Valuation uses the pharma sector profile.

Analyst read est. — computed against this company's niche peers in the same era. Inputs shown; not a quoted figure.

Fair
  • Modeled value is 1.17× the median modeled value of Series D+ Pharma companies in 2019–2021 (9 peers) — value vs value, same stage and era.
  • Within the normal band (117% of peer median) for its niche.
Dormant
  • Last raise 5.3 yr ago; this sector typically re-raises about every 16 months.
  • Silent for over 3× the sector's normal cadence.
Leadership

No named principal in this company's public records yet — see all operators below.

Explore how these operators interlock with other companies in the operator network.

Where it sits in Pharma

Pyxis Oncology, Inc. is one of 310 Pharma companies tracked from Cambridge. By capital raised it ranks among the largest (ahead of 96% of sector peers), and among the largest by modeled valuation est..

Ranking is computed against this company's own sector cohort — reported capital is fact; valuation tiers are modeled.

pharma

As reported in public records reported — not modeled.

US
Jurisdiction
Rule 506(b)
Reg D exemption
38
Investors (latest)
2018
Year incorporated
2021-03-05
First sale
Amount raised vs valuation, by round

Solid bars are reported offering amounts reported; hatched bars are the modeled post-money valuation est. — both on one shared scale so you can read raise-vs-worth at each round directly. Use the toggles to overlay data labels and the niche-peer / market average value lines.

Amount raised · realModeled valuation · estCumulative funded · real
$0$1.3B$2.5B$3.8B$5.0BSeries B · 2019-06-28 Raised $22M (real) Modeled valuation $748M (est)$22M$748MSeries B2019Series D+ · 2021-03-05 Raised $172M (real) Modeled valuation $5.0B (est)$172M$5.0BSeries D+2021+$172MCumulative $194M

The line shows cumulative reported funding over the period; + labels show new capital added between points when there is room. Toggle on-bar figures, plus the niche-peer and market averages, to read this company against its cohort. Benchmarks are modeled medians.

Financing ladder & sequence gaps
Series B$22.0M · 2019
Series D+$172.5M · 2021no Series C on file

Stages are modeled from round size (public records carry no series label). No record for: Pre-Seed, Seed, Series A, Series C — the company may have raised it under a different exemption, merged it into an adjacent record, or skipped it. Sequence completeness: 33%.

Modeled valuation trajectory
$5.0B
Base estimate est.
$821.1M
Conservative case
$10.1B
Upside case
$1.4B
Modeled post-money

Round size and date are reported; the stage label is inferred from round size (latest is Series D+a $100M–$400M round). Valuation is modeled from stage benchmarks scaled by the pharma sector profile. Directional, not a quoted figure.

Series B · modeled $748.1M · 2019-06-282019Series D+ · modeled $5.0B · 2021-03-052021
Model inputs · modeled:benchmark-stage-stepup-v1
12%
Dilution assumption
Implied ownership sold in the financing.
71%
Survival probability
57% low · 79% high
1.35×/yr
Annual markup
1.51×/yr upside case
5.3 yr
Elapsed time used
5.3 yr actual, capped for stale marks
pharma
Sector profile
Adjusts growth and survival by industry.
Financing rhythm
20 mo
Avg between rounds
$115.3M/yr
Capital velocity
7.0 yr
On record since
2019
First round
2
Rounds on file
How it compares to the market

Benchmarked against 310 companies in Pharma. Each bar is a median (the middle company, not an average — outliers don't skew it). Two yardsticks: real money raised (reported on Form D) and modeled value (our estimate est.). These are whole-sector medians across all stages, except the per-stage row.

Total raised — vs sector median (real $, all stages) 30× above median
This company$194.5M
Sector median$6.4M
Latest round — vs other Series D+ rounds in sector (real $, this stage) 1.4× above median
This company$172.5M
Sector median$125.0M
Modeled value — vs sector median (estimate, all stages) 80× above median
This company$5.0B
Sector median$62.5M

Raised more than 96% of sector peers (real $). Modeled value above 100% of peers (estimate).

Niche peers — same stage & era

A tighter cohort than the sector chart above — only companies at the same stage (Series D+) that last raised in the same ~3-year era, ranked by modeled value est. (not money raised). This is the exact set the analyst read compares against, so a like-for-like cohort is what makes "over/under-valued" meaningful. This company ranks #1 of 9.

This companyCohort peer
$1.0B$10.0B$10.0M$100.0M$1.0BCapital raised (log)Century Therapeutics, Inc. · Series D+ Raised $160.0M · modeled $4.7B (est)iTeos Therapeutics, Inc. · Series D+ Raised $125.4M · modeled $4.4B (est)SpringWorks Therapeutics, Inc. · Series D+ Raised $125.0M · modeled $4.4B (est)Nurix Therapeutics, Inc. · Series D+ Raised $144.7M · modeled $4.2B (est)Pear Therapeutics, Inc. · Series D+ Raised $254.8M · modeled $4.1B (est)Vor Biopharma Inc. · Series D+ Raised $110.1M · modeled $3.9B (est)Scribe Therapeutics, Inc. · Series D+ Raised $100.0M · modeled $2.9B (est)Compass Therapeutics, Inc. · Series D+ Raised $255.8M · modeled $2.1B (est)Pyxis Oncology, Inc. (this company) Raised $194.5M · modeled $5.0B (est)Pyxis Oncology, Inc.
CompanyStageRaised · realValue · estvs peer med.
Pyxis Oncology, Inc. this companySeries D+$194.5M$5.0B1.17×
Century Therapeutics, Inc.Series D+$160.0M$4.7B1.10×
iTeos Therapeutics, Inc.Series D+$125.4M$4.4B1.04×
SpringWorks Therapeutics, Inc.Series D+$125.0M$4.4B1.04×
Nurix Therapeutics, Inc.Series D+$144.7M$4.2B1.00×
Pear Therapeutics, Inc.Series D+$254.8M$4.1B0.97×
Vor Biopharma Inc.Series D+$110.1M$3.9B0.92×
Scribe Therapeutics, Inc.Series D+$100.0M$2.9B0.67×
Compass Therapeutics, Inc.Series D+$255.8M$2.1B0.50×
Full financing history

Stage is inferred from round size est., not reported on the filing — a round's dollar size maps to a bucket: Pre-Seed <$1.0M · Seed $1.0M–$4.0M · Series A $4.0M–$15M · Series B $15M–$40M · Series C $40M–$100M · Series D+ $100M–$400M · Growth/Late >$400M.

StageAmount · realAnnouncedPost-money · estValue · estConf.
Series B$22.0M2019-06-28$122.2M$748.1M90%
Series D+$172.5M2021-03-05$1.4B$5.0B90%
What happened at each round

Step-up, pace versus the sector's normal cadence, and revenue/exemption moves — read straight from the reported round facts reported.

  1. Series B$22.0M2019-06-28
    • First recorded raise — entered as Series B.
    • 9 investors on this round.
  2. Series D+$172.5M2021-03-05
    • Raised 20 mo later, in step with the ~16 mo sector norm.
    • Round 7.8× larger than the prior — scaling up.
    • 38 investors on this round.
Intelligence
2022 ~Q4
Modeled next raise · ~20mo cadence
$517.5M
Modeled next size est.range $336.4M$828.0M
7.8×
Last step-up
$115.3M/yr
Capital velocity

Predictive signals are modeled est. from this company's own cadence and step-up, plus sector benchmarks — directional, not advice. Peer set and a CSV export live in your analyst workspace.

Key people & operators

Officers, directors and promoters named in this company's public recordsreported — the people who run it (not its investors). "Also runs" counts come from name-matching across all records, so verify before acting.

PersonRoleAlso runsTied since
David Steinberg13 other2019-06
Christopher O'Donnell7 other2021-03
Christoph Westphal7 other2019-06
Geeta Vemuri6 other2019-06
Robert Crane6 other2021-03
Lucio Iannone5 other2019-06
Jak Knowles3 other2019-06
John Flavin3 other2019-06
Christian Schetter1 other2021-03
Gotham Makker2021-03
Lara Sullivan2021-03
Registry & provenance

Pyxis Oncology, Inc. is an official record sourced from the U.S. Securities and Exchange Commission (SEC). U.S. data is aggregated from SEC Form D filings.

United States
Country of record
US
Jurisdiction
1782223
SEC CIK
2018
Incorporated
Similar companies

Nearest neighbours across the whole database — matched on sector, stage and capital scale, and on shared operators (officers or directors named at both companies in public filings). A discovery shortlist, not a valuation cohort — verify before acting, the same way modeled figures are directional.

CompanySectorStageRaised · realValue · estWhy similar
Cognito Therapeutics Group, Inc.PharmaSeries D+$196.3M$1.7Bsame sector · same stage
Bright Peak Therapeutics, Inc.PharmaSeries D+$196.5M$1.0Bsame sector · same stage
Halda Therapeutics, LLCPharmaSeries D+$197.9M$1.3Bsame sector · same stage
Autolus Therapeutics plcPharmaSeries D+$200.0M$2.4Bsame sector · same stage
Candid Therapeutics, Inc.PharmaSeries D+$206.2M$2.1Bsame sector · same stage
Bluejay Therapeutics, Inc.PharmaSeries D+$221.7M$2.1Bsame sector · same stage
Affinia Therapeutics Inc.PharmaSeries D+$170.1M$99.8Msame sector · same stage
Century Therapeutics, Inc.PharmaSeries D+$160.0M$4.7Bsame sector · same stage
Semantically similar

Matched by meaning, not labels — a local language model reads each company's name, sector and description and ranks the closest in that learned space. This catches look-alikes that cross sector boundaries; the structured list above explains its matches, this one trusts the text. Directional, like every modeled signal here.

CompanySectorStageValue · estMatch
Pyx Health, Inc.HealthtechSeries A$207.2M85%
Pyx Health Holdings, LlcHealthtechSeries B$260.8M84%
Oncology Health Partners, LlcPharmaSeries A$62.6M84%
Fuse Oncology, Inc.PharmaSeries A$79.5M83%
Intera Oncology Inc.PharmaSeed$9.0M82%
Oncology Institute, Inc.Hospitals and PhysiciansSeries D+$144.8M81%
Elevation Oncology, Inc.PharmaSeries C$2.0B81%
Javelin Oncology, Inc.PharmaSeed$57.1M80%
Frequently asked
How much funding has Pyxis Oncology, Inc. raised?
Pyxis Oncology, Inc. has raised approximately $194.5M in disclosed capital across 2 recorded financing rounds, aggregated from public filings.
What is Pyxis Oncology, Inc.'s estimated valuation?
Provath's modeled valuation for Pyxis Oncology, Inc. is approximately $5.0B (modeled range $821.1M–$10.1B). This is an algorithmic estimate derived from round sizes and same-niche peers — not a quoted or reported figure.
What funding stage is Pyxis Oncology, Inc. at?
Pyxis Oncology, Inc.'s latest modeled financing stage is Series D+. Its most recent recorded round closed around Fri Mar 05.
What does Pyxis Oncology, Inc. do and where is it based?
Pyxis Oncology, Inc. operates in the Pharma sector, based in Cambridge.
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