Companies · Biotechnology

Prelude Therapeutics Inc

Wilmington · Biotechnology

Diligence memoA one-page analyst read on Prelude Therapeutics Inc — recommendation, valuation, rhythm, risks.
$115.0M
Total raised · real
4
Rounds
1.7×
Latest step-up
Top 10%
Sector rank · raised
Series C
Latest stage · inferred · Fri Aug 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time)

Prelude Therapeutics Inc looks fair against its niche peers and is dormant on financing cadence.

Synthesized from the figures below est. — every claim rests on a number shown on this page. Valuation uses the biotech sector profile.

Analyst read est. — computed against this company's niche peers in the same era. Inputs shown; not a quoted figure.

Fair
  • Modeled value is 1.00× the median modeled value of Series C Biotechnology companies in 2019–2021 (120 peers) — value vs value, same stage and era.
  • Within the normal band (100% of peer median) for its niche.
Dormant
  • Last raise 5.9 yr ago; this sector typically re-raises about every 14 months.
  • Silent for over 3× the sector's normal cadence.
Leadership

No named principal in this company's public records yet — see all operators below.

Explore how these operators interlock with other companies in the operator network.

Where it sits in Biotechnology

Prelude Therapeutics Inc is one of 4293 Biotechnology companies tracked from Wilmington. By capital raised it ranks among the largest (ahead of 91% of sector peers), and among the largest by modeled valuation est..

Ranking is computed against this company's own sector cohort — reported capital is fact; valuation tiers are modeled.

pharma

As reported in public records reported — not modeled.

US
Jurisdiction
Rule 506(b)
Reg D exemption
7
Investors (latest)
2016
Year incorporated
2020-08-21
First sale
Amount raised vs valuation, by round

Solid bars are reported offering amounts reported; hatched bars are the modeled post-money valuation est. — both on one shared scale so you can read raise-vs-worth at each round directly. Use the toggles to overlay data labels and the niche-peer / market average value lines.

Amount raised · realModeled valuation · estCumulative funded · real
$0$500M$1.0B$1.5B$2.0BSeries A · 2016-06-27 Raised $5.0M (real) Modeled valuation $181M (est)$5.0M$181MSeries A2016Series A · 2017-10-06 Raised $12M (real) Modeled valuation $434M (est)$12M$434MSeries A2017Series B · 2017-10-06 Raised $30M (real) Modeled valuation $1.2B (est)$30M$1.2BSeries B2017Series B · 2019-05-31 Raised $30M (real) Modeled valuation $1.2B (est)$30M$1.2BSeries B2019Series C · 2020-08-21 Raised $50M (real) Modeled valuation $1.9B (est)$50M$1.9BSeries C2020+$12M+$30M+$30M+$50MCumulative $127M

The line shows cumulative reported funding over the period; + labels show new capital added between points when there is room. Toggle on-bar figures, plus the niche-peer and market averages, to read this company against its cohort. Benchmarks are modeled medians.

Financing ladder & sequence gaps
Series A$5.0M · 2016
Series A extension$12.0M · 2017
Series B$30.0M · 2017
Series B extension$30.0M · 2019
Series C$50.0M · 2020

Stages are modeled from round size (public records carry no series label). No record for: Pre-Seed, Seed — the company may have raised it under a different exemption, merged it into an adjacent record, or skipped it. Sequence completeness: 60%.

Modeled valuation trajectory
$1.9B
Base estimate est.
$154.7M
Conservative case
$5.0B
Upside case
$333.3M
Modeled post-money

Round size and date are reported; the stage label is inferred from round size (latest is Series Ca $40M–$100M round). Valuation is modeled from stage benchmarks scaled by the biotech sector profile. Directional, not a quoted figure.

Series A · modeled $180.8M · 2016-06-272016Series A · modeled $433.8M · 2017-10-06Series B · modeled $1.2B · 2017-10-06Series B · modeled $1.2B · 2019-05-31Series C · modeled $1.9B · 2020-08-212020
Model inputs · modeled:benchmark-stage-stepup-v1
15%
Dilution assumption
Implied ownership sold in the financing.
62%
Survival probability
46% low · 72% high
1.46×/yr
Annual markup
1.68×/yr upside case
5.9 yr
Elapsed time used
5.9 yr actual, capped for stale marks
biotech
Sector profile
Adjusts growth and survival by industry.
Financing rhythm
12 mo
Avg between rounds
$27.7M/yr
Capital velocity
10.0 yr
On record since
2016
First round
5
Rounds on file
How it compares to the market

Benchmarked against 4293 companies in Biotechnology. Each bar is a median (the middle company, not an average — outliers don't skew it). Two yardsticks: real money raised (reported on Form D) and modeled value (our estimate est.). These are whole-sector medians across all stages, except the per-stage row.

Total raised — vs sector median (real $, all stages) 16× above median
This company$115.0M
Sector median$7.2M
Latest round — vs other Series C rounds in sector (real $, this stage) 1.1× above median
This company$50.0M
Sector median$46.5M
Modeled value — vs sector median (estimate, all stages) 30× above median
This company$1.9B
Sector median$64.2M

Raised more than 91% of sector peers (real $). Modeled value above 94% of peers (estimate).

Niche peers — same stage & era

A tighter cohort than the sector chart above — only companies at the same stage (Series C) that last raised in the same ~3-year era, ranked by modeled value est. (not money raised). This is the exact set the analyst read compares against, so a like-for-like cohort is what makes "over/under-valued" meaningful. This company ranks #61 of 120.

This companyCohort peer
$1.0B$10.0B$10.0M$100.0M$1.0BCapital raised (log)Stem Biotech LLC · Series C Raised $100.0M · modeled $4.1B (est)Kinnate Biopharma Inc. · Series C Raised $172.5M · modeled $3.9B (est)Arcutis Biotherapeutics, Inc. · Series C Raised $94.5M · modeled $3.9B (est)DNA Research INST LLC · Series C Raised $94.5M · modeled $3.7B (est)M3 Biotechnology, Inc. · Series C Raised $107.3M · modeled $3.6B (est)Checkmate Pharmaceuticals, Inc. · Series C Raised $185.1M · modeled $3.5B (est)Black Diamond Therapeutics, Inc. · Series C Raised $146.3M · modeled $3.5B (est)Finch Therapeutics Group, Inc. · Series C Raised $179.9M · modeled $3.5B (est)Shattuck Labs, Inc. · Series C Raised $165.4M · modeled $3.4B (est)TScan Therapeutics, Inc. · Series C Raised $123.3M · modeled $3.3B (est)Edgewise Therapeutics, Inc. · Series C Raised $120.1M · modeled $3.3B (est)Miragen Therapeutics, Inc. · Series C Raised $197.8M · modeled $3.3B (est)Prelude Therapeutics Inc (this company) Raised $115.0M · modeled $1.9B (est)Prelude Therapeutics Inc
CompanyStageRaised · realValue · estvs peer med.
Stem Biotech LLCSeries C$100.0M$4.1B2.11×
Kinnate Biopharma Inc.Series C$172.5M$3.9B2.02×
Arcutis Biotherapeutics, Inc.Series C$94.5M$3.9B1.99×
DNA Research INST LLCSeries C$94.5M$3.7B1.88×
M3 Biotechnology, Inc.Series C$107.3M$3.6B1.88×
Checkmate Pharmaceuticals, Inc.Series C$185.1M$3.5B1.79×
Black Diamond Therapeutics, Inc.Series C$146.3M$3.5B1.79×
Finch Therapeutics Group, Inc.Series C$179.9M$3.5B1.78×
Shattuck Labs, Inc.Series C$165.4M$3.4B1.75×
TScan Therapeutics, Inc.Series C$123.3M$3.3B1.72×
Edgewise Therapeutics, Inc.Series C$120.1M$3.3B1.70×
Miragen Therapeutics, Inc.Series C$197.8M$3.3B1.69×
Prelude Therapeutics Inc this companySeries C$115.0M$1.9B1.00×
Full financing history

Stage is inferred from round size est., not reported on the filing — a round's dollar size maps to a bucket: Pre-Seed <$1.0M · Seed $1.0M–$4.0M · Series A $4.0M–$15M · Series B $15M–$40M · Series C $40M–$100M · Series D+ $100M–$400M · Growth/Late >$400M.

StageAmount · realAnnouncedPost-money · estValue · estConf.
Series A$5.0M2016-06-27$22.7M$180.8M85%
Series A$12.0M2017-10-06$54.5M$433.8M90%
Series B$30.0M2017-10-06$166.7M$1.2B90%
Series B$30.0M2019-05-31$166.7M$1.2B90%
Series C$50.0M2020-08-21$333.3M$1.9B90%
What happened at each round

Step-up, pace versus the sector's normal cadence, and revenue/exemption moves — read straight from the reported round facts reported.

  1. Series A$5.0M2016-06-27
    • First recorded raise — entered as Series A.
    • 8 investors on this round.
  2. Series A$12.0M2017-10-06
    • Raised 15 mo later, in step with the ~14 mo sector norm.
    • Round 2.4× larger than the prior — scaling up.
    • 7 investors on this round.
  3. Series B$30.0M2017-10-06
    • Filed alongside the prior round (same month) — likely a tranche or amendment.
    • Round 2.5× larger than the prior — scaling up.
    • 7 investors on this round.
  4. Series B$30.0M2019-05-31
    • Raised 20 mo later, in step with the ~14 mo sector norm.
    • Round roughly the size of the prior one.
    • 6 investors on this round.
  5. Series C$50.0M2020-08-21
    • Raised 15 mo later, in step with the ~14 mo sector norm.
    • Round 1.7× larger than the prior — scaling up.
    • 7 investors on this round.
Intelligence
2021 ~Q3
Modeled next raise · ~12mo cadence
$83.3M
Modeled next size est.range $54.2M$133.3M
1.7×
Last step-up
$27.7M/yr
Capital velocity

Predictive signals are modeled est. from this company's own cadence and step-up, plus sector benchmarks — directional, not advice. Peer set and a CSV export live in your analyst workspace.

Key people & operators

Officers, directors and promoters named in this company's public recordsreported — the people who run it (not its investors). "Also runs" counts come from name-matching across all records, so verify before acting.

PersonRoleAlso runsTied since
David Bonita5 other2016-06
Paul Friedman4 other2016-06
David Mauro1 other2019-05
Mardi C. Dier1 other2020-08
Victor Sandor1 other2020-08
Andrew C. Combs2020-08
Brian C. Piper2020-08
Christopher C. Pierce2020-08
David C. Mauro2020-08
Deborah C. Morosini2020-08
Juan Luengo2017-10
Kelvin Neu2017-10
Krishna Vaddi2016-06
Peggy C. Scherle2020-08
Peggy Scherle2019-05
Registry & provenance

Prelude Therapeutics Inc is an official record sourced from the U.S. Securities and Exchange Commission (SEC). U.S. data is aggregated from SEC Form D filings.

United States
Country of record
US
Jurisdiction
1678660
SEC CIK
2016
Incorporated
Similar companies

Nearest neighbours across the whole database — matched on sector, stage and capital scale, and on shared operators (officers or directors named at both companies in public filings). A discovery shortlist, not a valuation cohort — verify before acting, the same way modeled figures are directional.

CompanySectorStageRaised · realValue · estWhy similar
Ikena Oncology, Inc.BiotechnologySeries C$117.6M$449.1Mnetwork1 shared operator · same sector · same stage
Adela, Inc.BiotechnologySeries C$108.5M$156.3Mnetwork1 shared operator · same sector · same stage
Enobia Pharma CorpBiotechnologySeries C$100.0M$819.2Mnetwork1 shared operator · same sector · same stage
Checkmate Pharmaceuticals, Inc.BiotechnologySeries C$185.1M$3.5Bnetwork1 shared operator · same sector · same stage
Foundation Medicine, Inc.BiotechnologySeries C$115.5M$2.3Bsame sector · same stage
Acrivon Therapeutics, Inc.BiotechnologySeries C$115.5M$2.4Bsame sector · same stage
Vineti, Inc.BiotechnologySeries C$115.7M$2.8Bsame sector · same stage
Magenta Therapeutics, Inc.BiotechnologySeries C$116.0M$2.1Bsame sector · same stage
Semantically similar

Matched by meaning, not labels — a local language model reads each company's name, sector and description and ranks the closest in that learned space. This catches look-alikes that cross sector boundaries; the structured list above explains its matches, this one trusts the text. Directional, like every modeled signal here.

CompanySectorStageValue · estMatch
Prelude CorpBiotechnologySeries A$13.8M93%
Vita Therapeutics, Inc.BiotechnologySeries B$461.5M83%
Capricor Therapeutics, Inc.BiotechnologySeries B$147.2M82%
Convergent Therapeutics, Inc.BiotechnologySeries B$153.1M82%
Dialectic Therapeutics, Inc.BiotechnologySeries A$184.2M82%
Apexian Pharmaceuticals, Inc.BiotechnologySeed$6.7M82%
Initial Therapeutics, Inc.BiotechnologySeed$168.6M82%
CARGO Therapeutics, Inc.BiotechnologySeries C$1.0B82%
Frequently asked
How much funding has Prelude Therapeutics Inc raised?
Prelude Therapeutics Inc has raised approximately $115.0M in disclosed capital across 4 recorded financing rounds, aggregated from public filings.
What is Prelude Therapeutics Inc's estimated valuation?
Provath's modeled valuation for Prelude Therapeutics Inc is approximately $1.9B (modeled range $154.7M–$5.0B). This is an algorithmic estimate derived from round sizes and same-niche peers — not a quoted or reported figure.
What funding stage is Prelude Therapeutics Inc at?
Prelude Therapeutics Inc's latest modeled financing stage is Series C. Its most recent recorded round closed around Fri Aug 21.
What does Prelude Therapeutics Inc do and where is it based?
Prelude Therapeutics Inc operates in the Biotechnology sector, based in Wilmington.
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