Companies · Biotechnology

Pique Therapeutics, Inc.

DURHAM · Biotechnology

Diligence memoA one-page analyst read on Pique Therapeutics, Inc. — recommendation, valuation, rhythm, risks.
$1.4M
Total raised · real
2
Rounds
1.6×
Latest step-up
Top 79%
Sector rank · raised
Pre-Seed
Latest stage · inferred · Mon Jul 31 2017 00:00:00 GMT+0000 (Coordinated Universal Time)

Pique Therapeutics, Inc. looks over-valued against its niche peers and is dormant on financing cadence.

Synthesized from the figures below est. — every claim rests on a number shown on this page. Valuation uses the biotech sector profile.

Analyst read est. — computed against this company's niche peers in the same era. Inputs shown; not a quoted figure.

Over-valued
  • Modeled value is 2.23× the median modeled value of Pre-Seed Biotechnology companies in 2016–2018 (152 peers) — value vs value, same stage and era.
  • Issuer reports no revenue, yet is modeled well above niche peers.
Dormant
  • Last raise 8.9 yr ago; this sector typically re-raises about every 14 months.
  • Silent for over 3× the sector's normal cadence.
Leadership

No named principal in this company's public records yet — see all operators below.

Explore how these operators interlock with other companies in the operator network.

Where it sits in Biotechnology

Pique Therapeutics, Inc. is one of 4291 Biotechnology companies tracked from DURHAM. By capital raised it ranks in the long tail (ahead of 22% of sector peers), and mid-pack by modeled valuation est..

Ranking is computed against this company's own sector cohort — reported capital is fact; valuation tiers are modeled.

pharma

As reported in public records reported — not modeled.

US
Jurisdiction
No revenue
Issuer revenue
Rule 504
Reg D exemption
13
Investors (latest)
2017-07-31
First sale
Amount raised vs valuation, by round

Solid bars are reported offering amounts reported; hatched bars are the modeled post-money valuation est. — both on one shared scale so you can read raise-vs-worth at each round directly. Use the toggles to overlay data labels and the niche-peer / market average value lines.

Amount raised · realModeled valuation · estCumulative funded · real
$0$13M$25M$38M$50MPre-Seed · 2009-05-22 Raised $536K (real) Modeled valuation $30M (est)$536K$30MPre-Seed2009Pre-Seed · 2017-07-31 Raised $854K (real) Modeled valuation $47M (est)$854K$47MPre-Seed2017+$854KCumulative $1.4M

The line shows cumulative reported funding over the period; + labels show new capital added between points when there is room. Toggle on-bar figures, plus the niche-peer and market averages, to read this company against its cohort. Benchmarks are modeled medians.

Financing ladder & sequence gaps
Pre-Seed$536K · 2009
Pre-Seed extension$854K · 2017

Stages are modeled from round size (public records carry no series label). Ladder is contiguous — every modeled rung has a record.

Modeled valuation trajectory
$47.2M
Base estimate est.
$456K
Conservative case
$534.7M
Upside case
$4.7M
Modeled post-money

Round size and date are reported; the stage label is inferred from round size (latest is Pre-Seeda round under $1.0M). Valuation is modeled from stage benchmarks scaled by the biotech sector profile. Directional, not a quoted figure.

Pre-Seed · modeled $29.6M · 2009-05-222009Pre-Seed · modeled $47.2M · 2017-07-312017
Model inputs · modeled:benchmark-stage-stepup-v1
18%
Dilution assumption
Implied ownership sold in the financing.
24%
Survival probability
10% low · 44% high
1.86×/yr
Annual markup
2.52×/yr upside case
6.0 yr
Elapsed time used
8.9 yr actual, capped for stale marks
biotech
Sector profile
Adjusts growth and survival by industry.
Financing rhythm
98 mo
Avg between rounds
$170K/yr
Capital velocity
17.1 yr
On record since
2009
First round
2
Rounds on file
How it compares to the market

Benchmarked against 4291 companies in Biotechnology. Each bar is a median (the middle company, not an average — outliers don't skew it). Two yardsticks: real money raised (reported on Form D) and modeled value (our estimate est.). These are whole-sector medians across all stages, except the per-stage row.

Total raised — vs sector median (real $, all stages) 0.2× of median
This company$1.4M
Sector median$7.2M
Latest round — vs other Pre-Seed rounds in sector (real $, this stage) 2.1× above median
This company$854K
Sector median$412K
Modeled value — vs sector median (estimate, all stages) 0.7× of median
This company$47.2M
Sector median$64.2M

Raised more than 22% of sector peers (real $). Modeled value above 44% of peers (estimate).

Niche peers — same stage & era

A tighter cohort than the sector chart above — only companies at the same stage (Pre-Seed) that last raised in the same ~3-year era, ranked by modeled value est. (not money raised). This is the exact set the analyst read compares against, so a like-for-like cohort is what makes "over/under-valued" meaningful. This company ranks #11 of 152.

This companyCohort peer
$10.0M$100.0M$100K$1.0M$10.0MCapital raised (log)Cerebral Magnetics INC · Pre-Seed Raised $1.0M · modeled $55.2M (est)AnTolRx, Inc. · Pre-Seed Raised $1.0M · modeled $55.2M (est)NutriBand Inc. · Pre-Seed Raised $1.2M · modeled $55.2M (est)US Biologic, Inc. · Pre-Seed Raised $1.0M · modeled $55.2M (est)New Vital Signs, Inc. · Pre-Seed Raised $1.0M · modeled $55.2M (est)Jivana Biotechnology Inc · Pre-Seed Raised $2.0M · modeled $55.2M (est)Zeta Biolongevity, Inc. · Pre-Seed Raised $995K · modeled $54.9M (est)ALRGN Bio, Inc. · Pre-Seed Raised $946K · modeled $52.2M (est)BioSurfaces, LLC · Pre-Seed Raised $900K · modeled $49.7M (est)Cellsolutions Llc · Pre-Seed Raised $1.9M · modeled $49.7M (est)NeuExCell Therapeutics Inc. · Pre-Seed Raised $850K · modeled $46.9M (est)Pique Therapeutics, Inc. (this company) Raised $1.4M · modeled $47.2M (est)Pique Therapeutics, Inc.
CompanyStageRaised · realValue · estvs peer med.
Cerebral Magnetics INCPre-Seed$1.0M$55.2M2.61×
AnTolRx, Inc.Pre-Seed$1.0M$55.2M2.61×
NutriBand Inc.Pre-Seed$1.2M$55.2M2.61×
US Biologic, Inc.Pre-Seed$1.0M$55.2M2.61×
New Vital Signs, Inc.Pre-Seed$1.0M$55.2M2.61×
Jivana Biotechnology IncPre-Seed$2.0M$55.2M2.61×
Zeta Biolongevity, Inc.Pre-Seed$995K$54.9M2.60×
ALRGN Bio, Inc.Pre-Seed$946K$52.2M2.47×
BioSurfaces, LLCPre-Seed$900K$49.7M2.35×
Cellsolutions LlcPre-Seed$1.9M$49.7M2.35×
Pique Therapeutics, Inc. this companyPre-Seed$1.4M$47.2M2.23×
NeuExCell Therapeutics Inc.Pre-Seed$850K$46.9M2.22×
Full financing history

Stage is inferred from round size est., not reported on the filing — a round's dollar size maps to a bucket: Pre-Seed <$1.0M · Seed $1.0M–$4.0M · Series A $4.0M–$15M · Series B $15M–$40M · Series C $40M–$100M · Series D+ $100M–$400M · Growth/Late >$400M.

StageAmount · realAnnouncedPost-money · estValue · estConf.
Pre-Seed$536K2009-05-22$3.0M$29.6M85%
Pre-Seed$854K2017-07-31$4.7M$47.2M90%
What happened at each round

Step-up, pace versus the sector's normal cadence, and revenue/exemption moves — read straight from the reported round facts reported.

  1. Pre-Seed$536K2009-05-22
    • First recorded raise — entered as Pre-Seed.
    • 7 investors on this round.
  2. Pre-Seed$854K2017-07-31
    • Raised again after 98 mo — slower than the ~14 mo sector norm.
    • Round 1.6× larger than the prior — scaling up.
    • Switched to Rule 504 (was Rule 06).
    • 13 investors on this round.
Intelligence
2025 ~Q4
Modeled next raise · ~98mo cadence
$1.4M
Modeled next size est.range $886K$2.2M
1.6×
Last step-up
$170K/yr
Capital velocity

Predictive signals are modeled est. from this company's own cadence and step-up, plus sector benchmarks — directional, not advice. Peer set and a CSV export live in your analyst workspace.

Key people & operators

Officers, directors and promoters named in this company's public recordsreported — the people who run it (not its investors). "Also runs" counts come from name-matching across all records, so verify before acting.

PersonRoleAlso runsTied since
Keith Dionne2 other2017-07
Christopher Meldrum1 other2009-05
Ian J. Mehr2017-07
John B. Brennan2017-07
Registry & provenance

Pique Therapeutics, Inc. is an official record sourced from the U.S. Securities and Exchange Commission (SEC). U.S. data is aggregated from SEC Form D filings.

United States
Country of record
US
Jurisdiction
1465515
SEC CIK
Similar companies

Nearest neighbours across the whole database — matched on sector, stage and capital scale, and on shared operators (officers or directors named at both companies in public filings). A discovery shortlist, not a valuation cohort — verify before acting, the same way modeled figures are directional.

CompanySectorStageRaised · realValue · estWhy similar
Analyte Logic CorpBiotechnologyPre-Seed$1.4M$38.6Msame sector · same stage
Diffinity Genomics IncBiotechnologyPre-Seed$1.4M$37.4Msame sector · same stage
Kika Medical International CoBiotechnologyPre-Seed$1.3M$46.9Msame sector · same stage
Vicus Therapeutics LlcBiotechnologyPre-Seed$1.4M$41.7Msame sector · same stage
Prime Genomics, Inc.BiotechnologyPre-Seed$1.3M$44.4Msame sector · same stage
Immunetics, Inc.BiotechnologyPre-Seed$1.5M$46.1Msame sector · same stage
Alchemia Oncology Pty LtdBiotechnologyPre-Seed$1.3M$39.1Msame sector · same stage
Koronis Pharma, Inc.BiotechnologyPre-Seed$1.3M$55.2Msame sector · same stage
Semantically similar

Matched by meaning, not labels — a local language model reads each company's name, sector and description and ranks the closest in that learned space. This catches look-alikes that cross sector boundaries; the structured list above explains its matches, this one trusts the text. Directional, like every modeled signal here.

CompanySectorStageValue · estMatch
Ptc Therapeutics, Inc.BiotechnologySeries D+$591.1M85%
Pi Health Inc.BiotechnologySeries C$421.7M85%
Rasna Therapeutics Inc.BiotechnologySeed$89.7M84%
Pirouette Medical Inc.BiotechnologySeries A$2.5M84%
Vita Therapeutics, Inc.BiotechnologySeries B$461.0M84%
Pahr Therapeutics, Inc.BiotechnologySeries A$17.8M83%
Pharmesol Inc.BiotechnologySeed$4.2M83%
Rasio Therapeutics, Inc.BiotechnologySeed$31.2M83%
Frequently asked
How much funding has Pique Therapeutics, Inc. raised?
Pique Therapeutics, Inc. has raised approximately $1.4M in disclosed capital across 2 recorded financing rounds, aggregated from public filings.
What is Pique Therapeutics, Inc.'s estimated valuation?
Provath's modeled valuation for Pique Therapeutics, Inc. is approximately $47.2M (modeled range $456K–$534.7M). This is an algorithmic estimate derived from round sizes and same-niche peers — not a quoted or reported figure.
What funding stage is Pique Therapeutics, Inc. at?
Pique Therapeutics, Inc.'s latest modeled financing stage is Pre-Seed. Its most recent recorded round closed around Mon Jul 31.
What does Pique Therapeutics, Inc. do and where is it based?
Pique Therapeutics, Inc. operates in the Biotechnology sector, based in DURHAM.
Explore related

See where Pique Therapeutics, Inc. sits in the wider market — its sector, location and stage cohorts, each with their own leaderboards and capital-flow timelines.

Is this your company?

If you work at Pique Therapeutics, Inc., claim this profile or suggest a correction. We aggregate from public filings, so help us keep your description, website and links accurate.

Is this your company? Update your profile or add contact details — and choose exactly who can reach you. Reviewed before anything is published.