Companies · Biotech

Orpheus Bioscience, Inc.

MANASSAS · Biotech · refined from filed group “Other

Diligence memoA one-page analyst read on Orpheus Bioscience, Inc. — recommendation, valuation, rhythm, risks.
$4.4M
Total raised · real
2
Rounds
2.5×
Latest step-up
Top 22%
Sector rank · raised
Seed
Latest stage · inferred · Tue Jun 11 2019 00:00:00 GMT+0000 (Coordinated Universal Time)

Orpheus Bioscience, Inc. looks over-valued against its niche peers and is dormant on financing cadence.

Synthesized from the figures below est. — every claim rests on a number shown on this page. Valuation uses the biotech sector profile.

Analyst read est. — computed against this company's niche peers in the same era. Inputs shown; not a quoted figure.

Over-valued
  • Modeled value is 1.59× the median modeled value of Seed Biotech companies in 2019–2021 (7 peers) — value vs value, same stage and era.
Dormant
  • Last raise 7.1 yr ago; this sector typically re-raises about every 11 months.
  • Silent for over 3× the sector's normal cadence.
Leadership

No named principal in this company's public records yet — see all operators below.

Explore how these operators interlock with other companies in the operator network.

Where it sits in Biotech

Orpheus Bioscience, Inc. is one of 233 Biotech companies tracked from MANASSAS. By capital raised it ranks in the upper tier (ahead of 79% of sector peers), and among the largest by modeled valuation est..

Ranking is computed against this company's own sector cohort — reported capital is fact; valuation tiers are modeled.

biotech

As reported in public records reported — not modeled.

US
Jurisdiction
Rule 506(b)
Reg D exemption
38
Investors (latest)
2017
Year incorporated
2019-06-11
First sale
Amount raised vs valuation, by round

Solid bars are reported offering amounts reported; hatched bars are the modeled post-money valuation est. — both on one shared scale so you can read raise-vs-worth at each round directly. Use the toggles to overlay data labels and the niche-peer / market average value lines.

Amount raised · realModeled valuation · estCumulative funded · real
$0$50M$100M$150M$200MSeed · 2017-05-09 Raised $1.5M (real) Modeled valuation $65M (est)$1.5M$65MSeed2017Seed · 2017-05-23 Raised $1.3M (real) Modeled valuation $56M (est)$1.3M$56MSeed2017Seed · 2017-05-23 Raised $1.3M (real) Modeled valuation $56M (est)$1.3M$56MSeed2017Seed · 2019-06-11 Raised $3.2M (real) Modeled valuation $140M (est)$3.2M$140MSeed2019+$1.3M+$1.3M+$3.2MCumulative $7.1M

The line shows cumulative reported funding over the period; + labels show new capital added between points when there is room. Toggle on-bar figures, plus the niche-peer and market averages, to read this company against its cohort. Benchmarks are modeled medians.

Financing ladder & sequence gaps
Seed$1.5M · 2017
Seed extension$1.3M · 2017
Seed extension$1.3M · 2017
Seed extension$3.2M · 2019

Stages are modeled from round size (public records carry no series label). No record for: Pre-Seed — the company may have raised it under a different exemption, merged it into an adjacent record, or skipped it. Sequence completeness: 50%.

Modeled valuation trajectory
$140.2M
Base estimate est.
$2.3M
Conservative case
$1.1B
Upside case
$15.8M
Modeled post-money

Round size and date are reported; the stage label is inferred from round size (latest is Seeda $1.0M–$4.0M round). Valuation is modeled from stage benchmarks scaled by the biotech sector profile. Directional, not a quoted figure.

Seed · modeled $64.6M · 2017-05-092017Seed · modeled $55.7M · 2017-05-23Seed · modeled $55.7M · 2017-05-23Seed · modeled $140.2M · 2019-06-112019
Model inputs · modeled:benchmark-stage-stepup-v1
20%
Dilution assumption
Implied ownership sold in the financing.
32%
Survival probability
14% low · 50% high
1.74×/yr
Annual markup
2.28×/yr upside case
6.0 yr
Elapsed time used
7.1 yr actual, capped for stale marks
biotech
Sector profile
Adjusts growth and survival by industry.
Financing rhythm
8 mo
Avg between rounds
$2.1M/yr
Capital velocity
9.1 yr
On record since
2017
First round
4
Rounds on file
How it compares to the market

Benchmarked against 233 companies in Biotech. Each bar is a median (the middle company, not an average — outliers don't skew it). Two yardsticks: real money raised (reported on Form D) and modeled value (our estimate est.). These are whole-sector medians across all stages, except the per-stage row.

Total raised — vs sector median (real $, all stages) 0.6× of median
This company$4.4M
Sector median$7.8M
Latest round — vs other Seed rounds in sector (real $, this stage) 2.7× above median
This company$3.2M
Sector median$1.2M
Modeled value — vs sector median (estimate, all stages) 2.5× above median
This company$140.2M
Sector median$56.1M

Raised more than 79% of sector peers (real $). Modeled value above 91% of peers (estimate).

Niche peers — same stage & era

A tighter cohort than the sector chart above — only companies at the same stage (Seed) that last raised in the same ~3-year era, ranked by modeled value est. (not money raised). This is the exact set the analyst read compares against, so a like-for-like cohort is what makes "over/under-valued" meaningful. This company ranks #1 of 7.

This companyCohort peer
$10.0M$100.0M$1.0B$1.0M$10.0MCapital raised (log)OneThree Biotech, Inc. · Seed Raised $2.8M · modeled $124.4M (est)Phloem Biotech, Inc. · Seed Raised $2.7M · modeled $118.7M (est)Meridian Biotech, LLC · Seed Raised $3.9M · modeled $88.0M (est)Sixfold Bioscience Inc. · Seed Raised $2.3M · modeled $70.2M (est)iGenomX International Genomics Corp · Seed Raised $5.1M · modeled $66.7M (est)KelSie Biotech Corp · Seed Raised $3.3M · modeled $40.2M (est)Orpheus Bioscience, Inc. (this company) Raised $4.4M · modeled $140.2M (est)Orpheus Bioscience, Inc.
CompanyStageRaised · realValue · estvs peer med.
Orpheus Bioscience, Inc. this companySeed$4.4M$140.2M1.59×
OneThree Biotech, Inc.Seed$2.8M$124.4M1.41×
Phloem Biotech, Inc.Seed$2.7M$118.7M1.35×
Meridian Biotech, LLCSeed$3.9M$88.0M1.00×
Sixfold Bioscience Inc.Seed$2.3M$70.2M0.80×
iGenomX International Genomics CorpSeed$5.1M$66.7M0.76×
KelSie Biotech CorpSeed$3.3M$40.2M0.46×
Full financing history

Stage is inferred from round size est., not reported on the filing — a round's dollar size maps to a bucket: Pre-Seed <$1.0M · Seed $1.0M–$4.0M · Series A $4.0M–$15M · Series B $15M–$40M · Series C $40M–$100M · Series D+ $100M–$400M · Growth/Late >$400M.

StageAmount · realAnnouncedPost-money · estValue · estConf.
Seed$1.5M2017-05-09$7.3M$64.6M90%
Seed$1.3M2017-05-23$6.3M$55.7M90%
Seed$1.3M2017-05-23$6.3M$55.7M90%
Seed$3.2M2019-06-11$15.8M$140.2M90%
What happened at each round

Step-up, pace versus the sector's normal cadence, and revenue/exemption moves — read straight from the reported round facts reported.

  1. Seed$1.5M2017-05-09
    • First recorded raise — entered as Seed.
    • 20 investors on this round.
  2. Seed$1.3M2017-05-23
    • Filed alongside the prior round (same month) — likely a tranche or amendment.
    • Round roughly the size of the prior one.
    • 20 investors on this round.
  3. Seed$1.3M2017-05-23
    • Filed alongside the prior round (same month) — likely a tranche or amendment.
    • Round roughly the size of the prior one.
    • 20 investors on this round.
  4. Seed$3.2M2019-06-11
    • Raised again after 25 mo — slower than the ~11 mo sector norm.
    • Round 2.5× larger than the prior — scaling up.
    • 38 investors on this round.
Intelligence
2020 ~Q1
Modeled next raise · ~8mo cadence
$7.9M
Modeled next size est.range $5.2M$12.7M
2.5×
Last step-up
$2.1M/yr
Capital velocity

Predictive signals are modeled est. from this company's own cadence and step-up, plus sector benchmarks — directional, not advice. Peer set and a CSV export live in your analyst workspace.

Key people & operators

Officers, directors and promoters named in this company's public recordsreported — the people who run it (not its investors). "Also runs" counts come from name-matching across all records, so verify before acting.

PersonRoleAlso runsTied since
Guy Yachin3 other2017-05
John Abeles3 other2017-05
Cohava Gelber1 other2017-05
Registry & provenance

Orpheus Bioscience, Inc. is an official record sourced from the U.S. Securities and Exchange Commission (SEC). U.S. data is aggregated from SEC Form D filings.

United States
Country of record
US
Jurisdiction
1707212
SEC CIK
2017
Incorporated
Similar companies

Nearest neighbours across the whole database — matched on sector, stage and capital scale, and on shared operators (officers or directors named at both companies in public filings). A discovery shortlist, not a valuation cohort — verify before acting, the same way modeled figures are directional.

CompanySectorStageRaised · realValue · estWhy similar
Retrieve Medical Holdings, Inc.HealthtechSeed$2.3M$8.1Mnetwork2 shared operators · same stage
General Genomics Inc.BiotechSeed$4.0M$14.1Msame sector · same stage
Meridian Biotech, LLCBiotechSeed$3.9M$88.0Msame sector · same stage
Ambra Bioscience LLCBiotechSeed$3.8M$46.6Msame sector · same stage
iGenomX International Genomics CorpBiotechSeed$5.1M$66.7Msame sector · same stage
J3 Bioscience, Inc.BiotechSeed$5.5M$7.4Msame sector · same stage
KelSie Biotech CorpBiotechSeed$3.3M$40.2Msame sector · same stage
YemaachiBiotechSeed$3.0M$51.0Msame sector · same stage
Semantically similar

Matched by meaning, not labels — a local language model reads each company's name, sector and description and ranks the closest in that learned space. This catches look-alikes that cross sector boundaries; the structured list above explains its matches, this one trusts the text. Directional, like every modeled signal here.

CompanySectorStageValue · estMatch
Ora Biomedical, Inc.BiotechnologyPre-Seed$4.4M83%
ORF Biologics, Inc.BiotechnologySeed$9.4M83%
Orna Therapeutics Holdings, LLCBiotechnologySeries D+$2.5B82%
Ark Biotech Inc.BiotechSeries A$46.0M82%
Animal Biosciences, Inc.Biotech / PharmaSeed$31.6M81%
Empire Biotechnologies, Inc.Biotech / PharmaPre-Seed$5.6M81%
Verix Health, Inc.BiotechnologySeed$66.6M81%
Biotech Social Inc.BiotechPre-Seed$1.4M81%
Frequently asked
How much funding has Orpheus Bioscience, Inc. raised?
Orpheus Bioscience, Inc. has raised approximately $4.4M in disclosed capital across 2 recorded financing rounds, aggregated from public filings.
What is Orpheus Bioscience, Inc.'s estimated valuation?
Provath's modeled valuation for Orpheus Bioscience, Inc. is approximately $140.2M (modeled range $2.3M–$1.1B). This is an algorithmic estimate derived from round sizes and same-niche peers — not a quoted or reported figure.
What funding stage is Orpheus Bioscience, Inc. at?
Orpheus Bioscience, Inc.'s latest modeled financing stage is Seed. Its most recent recorded round closed around Tue Jun 11.
What does Orpheus Bioscience, Inc. do and where is it based?
Orpheus Bioscience, Inc. operates in the Biotech sector, based in MANASSAS.
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