Diligence memo · auto-generated · as of July 2, 2026

OnKure, Inc.

OnKure, Inc. looks fair against its niche peers and is at-risk on financing cadence.

WatchOverdue for a raise versus sector cadence — could be a bridge, a down round, or distress. Watch for the next filing.

Businessfiled

OnKure, Inc. operates in Pharmaceuticals, based in BOULDER.

No verified homepage on file yet — operating evidence is limited to the public record.

Capital & rounds (filed)filed

OnKure, Inc. has raised $123M in disclosed capital across 10 recorded rounds, aggregated from public filings. Its latest round is modeled as Series C (a $40M–$100M round).

Largest single filing: $57M on 2021-03-03.

Most recent recorded round closed around 2023-03-24.

Valuation (modeled)modeled

Provath models OnKure, Inc. at approximately $732M (range $175M–$1.3B). This is an algorithmic estimate from round sizes and same-niche peers — not a quoted or reported figure.

Read: Fair. Modeled value is 1.27× the median modeled value of Series C Pharmaceuticals companies in 2022–2024 (30 peers) — value vs value, same stage and era. Within the normal band (127% of peer median) for its niche.

Financing rhythm & timingmixed

Historic cadence: a new round about every 11 months.

Last raise 3.3 yr ago; this sector typically re-raises about every 13 months.

Past due for a raise versus sector cadence — watch for distress or a bridge.

The last round was 1.1× smaller than the prior — a bridge or down round.

Comparablesmixed

Capital scale ranks ahead of 93% of Pharmaceuticals peers (1613 compared).

Modeled value ranks above 85% of those peers.

Closest niche peers: Vigil Neuroscience, Inc., Leap Therapeutics, Inc., Alimera Sciences Inc, VYNE Therapeutics Inc., Lusaris Therapeutics, Inc..

Peoplefiled

21 named people on file across officers, directors and signatories.

Risks & flagsmixed

Overdue for a raise versus sector norm — distress or bridge risk.

No clearly named CEO/founder/principal in the surfaced records — key-person evidence is thin.