Companies · Pharma

Nuo Therapeutics, Inc.

Houston · Pharma · refined from filed group “Other Health Care

Diligence memoA one-page analyst read on Nuo Therapeutics, Inc. — recommendation, valuation, rhythm, risks.
$46.3M
Total raised · real
16
Rounds
0.9×
Latest step-up
Top 16%
Sector rank · raised
Series B
Latest stage · inferred · Wed Jul 30 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

Nuo Therapeutics, Inc. looks under-valued against its niche peers and is active on financing cadence.

Synthesized from the figures below est. — every claim rests on a number shown on this page. Valuation uses the pharma sector profile.

Analyst read est. — computed against this company's niche peers in the same era. Inputs shown; not a quoted figure.

Under-valued
  • Modeled value is 0.04× the median modeled value of Series B Pharma companies in 2025–2027 (8 peers) — value vs value, same stage and era.
Active
  • Last raise 11 mo ago; this sector typically re-raises about every 16 months.
  • Raising on or ahead of the sector's normal rhythm.
Leadership

No named principal in this company's public records yet — see all operators below.

Explore how these operators interlock with other companies in the operator network.

Where it sits in Pharma

Nuo Therapeutics, Inc. is one of 310 Pharma companies tracked from Houston. By capital raised it ranks in the upper tier (ahead of 85% of sector peers), and in the long tail by modeled valuation est..

Ranking is computed against this company's own sector cohort — reported capital is fact; valuation tiers are modeled.

pharma

As reported in public records reported — not modeled.

US
Jurisdiction
Rule 506(b)
Reg D exemption
9
Investors (latest)
2025-07-30
First sale
Amount raised vs valuation, by round

Solid bars are reported offering amounts reported; hatched bars are the modeled post-money valuation est. — both on one shared scale so you can read raise-vs-worth at each round directly. Use the toggles to overlay data labels and the niche-peer / market average value lines.

Amount raised · realModeled valuation · estCumulative funded · real
$0$250M$500M$750M$1.0BSeed · 2010-04-09 Raised $3.6M (real) Modeled valuation $139M (est)Seed2010Seed · 2010-10-05 Raised $147K (real) Modeled valuation $5.6M (est)Seed2010Seed · 2011-04-29 Raised $325K (real) Modeled valuation $12M (est)Seed2011Seed · 2011-07-15 Raised $1.3M (real) Modeled valuation $49M (est)Seed2011Seed · 2011-07-15 Raised $600K (real) Modeled valuation $23M (est)Seed2011Series B · 2012-02-08 Raised $21M (real) Modeled valuation $714M (est)Series B2012Series B · 2013-12-02 Raised $3.0M (real) Modeled valuation $102M (est)Series B2013Series B · 2016-05-05 Raised $7.5M (real) Modeled valuation $255M (est)Series B2016Series B · 2018-05-28 Raised $500K (real) Modeled valuation $17M (est)Series B2018Series B · 2022-04-29 Raised $3.5M (real) Modeled valuation $59M (est)Series B2022Series B · 2022-05-18 Raised $408K (real) Modeled valuation $6.6M (est)Series B2022Series B · 2023-08-01 Raised $1.0M (real) Modeled valuation $10M (est)Series B2023Series B · 2023-12-19 Raised $963K (real) Modeled valuation $8.3M (est)Series B2023Series B · 2024-05-20 Raised $651K (real) Modeled valuation $4.8M (est)Series B2024Series B · 2024-09-19 Raised $849K (real) Modeled valuation $5.5M (est)Series B2024Series B · 2025-07-30 Raised $791K (real) Modeled valuation $3.6M (est)Series B2025Cumulative $46M

The line shows cumulative reported funding over the period; + labels show new capital added between points when there is room. Toggle on-bar figures, plus the niche-peer and market averages, to read this company against its cohort. Benchmarks are modeled medians.

Financing ladder & sequence gaps
Seed$3.6M · 2010
Seed extension$147K · 2010
Seed extension$325K · 2011
Seed extension$1.3M · 2011
Seed extension$600K · 2011
Series B$21.0M · 2012no Series A on file
Series B extension$3.0M · 2013
Series B extension$7.5M · 2016
Series B extension$500K · 2018
Series B extension$3.5M · 2022
Series B extension$408K · 2022
Series B extension$1.0M · 2023
Series B extension$963K · 2023
Series B extension$651K · 2024
Series B extension$849K · 2024
Series B extension$791K · 2025

Stages are modeled from round size (public records carry no series label). No record for: Pre-Seed, Series A — the company may have raised it under a different exemption, merged it into an adjacent record, or skipped it. Sequence completeness: 50%.

Modeled valuation trajectory
$3.6M
Base estimate est.
$1.7M
Conservative case
$5.3M
Upside case
$4.4M
Modeled post-money

Round size and date are reported; the stage label is inferred from round size (latest is Series Ba $15M–$40M round). Valuation is modeled from stage benchmarks scaled by the pharma sector profile. Directional, not a quoted figure.

Seed · modeled $138.9M · 2010-04-092010Seed · modeled $5.6M · 2010-10-05Seed · modeled $12.4M · 2011-04-29Seed · modeled $49.5M · 2011-07-15Seed · modeled $22.8M · 2011-07-15Series B · modeled $714.1M · 2012-02-08Series B · modeled $102.0M · 2013-12-02Series B · modeled $255.0M · 2016-05-05Series B · modeled $17.0M · 2018-05-28Series B · modeled $58.7M · 2022-04-29Series B · modeled $6.6M · 2022-05-18Series B · modeled $10.4M · 2023-08-01Series B · modeled $8.3M · 2023-12-19Series B · modeled $4.8M · 2024-05-20Series B · modeled $5.5M · 2024-09-19Series B · modeled $3.6M · 2025-07-302025
Model inputs · modeled:benchmark-stage-stepup-v1
18%
Dilution assumption
Implied ownership sold in the financing.
57%
Survival probability
38% low · 70% high
1.49×/yr
Annual markup
1.80×/yr upside case
0.9 yr
Elapsed time used
0.9 yr actual, capped for stale marks
pharma
Sector profile
Adjusts growth and survival by industry.
Financing rhythm
12 mo
Avg between rounds
$3.0M/yr
Capital velocity
16.2 yr
On record since
2010
First round
16
Rounds on file
How it compares to the market

Benchmarked against 310 companies in Pharma. Each bar is a median (the middle company, not an average — outliers don't skew it). Two yardsticks: real money raised (reported on Form D) and modeled value (our estimate est.). These are whole-sector medians across all stages, except the per-stage row.

Total raised — vs sector median (real $, all stages) 7.2× above median
This company$46.3M
Sector median$6.4M
Latest round — vs other Series B rounds in sector (real $, this stage) 0.0× of median
This company$791K
Sector median$19.0M
Modeled value — vs sector median (estimate, all stages) 0.1× of median
This company$3.6M
Sector median$62.5M

Raised more than 85% of sector peers (real $). Modeled value above 25% of peers (estimate).

Niche peers — same stage & era

A tighter cohort than the sector chart above — only companies at the same stage (Series B) that last raised in the same ~3-year era, ranked by modeled value est. (not money raised). This is the exact set the analyst read compares against, so a like-for-like cohort is what makes "over/under-valued" meaningful. This company ranks #8 of 8.

This companyCohort peer
$1.0M$10.0M$100.0M$1.0B$10.0M$100.0MCapital raised (log)Juvena Therapeutics, Inc. · Series B Raised $34.8M · modeled $144.4M (est)Alessa Therapeutics, Inc. · Series B Raised $31.6M · modeled $129.6M (est)Amani Therapeutics, Inc. · Series B Raised $31.1M · modeled $125.2M (est)Shenandoah Therapeutics Inc. · Series B Raised $21.5M · modeled $108.2M (est)Atlas Oncology Holdings Inc. · Series B Raised $23.0M · modeled $85.1M (est)TwoStep Therapeutics, Inc. · Series B Raised $27.6M · modeled $80.9M (est)CHARM Therapeutics Inc. · Series B Raised $87.0M · modeled $77.3M (est)Nuo Therapeutics, Inc. (this company) Raised $46.3M · modeled $3.6M (est)Nuo Therapeutics, Inc.
CompanyStageRaised · realValue · estvs peer med.
Juvena Therapeutics, Inc.Series B$34.8M$144.4M1.49×
Alessa Therapeutics, Inc.Series B$31.6M$129.6M1.34×
Amani Therapeutics, Inc.Series B$31.1M$125.2M1.30×
Shenandoah Therapeutics Inc.Series B$21.5M$108.2M1.12×
Atlas Oncology Holdings Inc.Series B$23.0M$85.1M0.88×
TwoStep Therapeutics, Inc.Series B$27.6M$80.9M0.84×
CHARM Therapeutics Inc.Series B$87.0M$77.3M0.80×
Nuo Therapeutics, Inc. this companySeries B$46.3M$3.6M0.04×
Full financing history

Stage is inferred from round size est., not reported on the filing — a round's dollar size maps to a bucket: Pre-Seed <$1.0M · Seed $1.0M–$4.0M · Series A $4.0M–$15M · Series B $15M–$40M · Series C $40M–$100M · Series D+ $100M–$400M · Growth/Late >$400M.

StageAmount · realAnnouncedPost-money · estValue · estConf.
Seed$3.6M2010-04-09$18.3M$138.9M85%
Seed$147K2010-10-05$734K$5.6M85%
Seed$325K2011-04-29$1.6M$12.4M85%
Seed$1.3M2011-07-15$6.5M$49.5M85%
Seed$600K2011-07-15$3.0M$22.8M85%
Series B$21.0M2012-02-08$116.7M$714.1M85%
Series B$3.0M2013-12-02$16.7M$102.0M85%
Series B$7.5M2016-05-05$41.7M$255.0M85%
Series B$500K2018-05-28$2.8M$17.0M90%
Series B$3.5M2022-04-29$19.7M$58.7M90%
Series B$408K2022-05-18$2.3M$6.6M90%
Series B$1.0M2023-08-01$5.8M$10.4M90%
Series B$963K2023-12-19$5.3M$8.3M90%
Series B$651K2024-05-20$3.6M$4.8M90%
Series B$849K2024-09-19$4.7M$5.5M90%
Series B$791K2025-07-30$4.4M$3.6M90%
What happened at each round

Step-up, pace versus the sector's normal cadence, and revenue/exemption moves — read straight from the reported round facts reported.

  1. Seed$3.6M2010-04-09
    • First recorded raise — entered as Seed.
    • 18 investors on this round.
  2. Seed$147K2010-10-05
    • Came back fast: 6 mo vs the ~16 mo sector norm.
    • Round 24.9× smaller than the prior — bridge or down round.
    • 1 investor on this round.
  3. Seed$325K2011-04-29
    • Came back fast: 7 mo vs the ~16 mo sector norm.
    • Round 2.2× larger than the prior — scaling up.
    • 4 investors on this round.
  4. Seed$1.3M2011-07-15
    • Came back fast: 3 mo vs the ~16 mo sector norm.
    • Round 4.0× larger than the prior — scaling up.
    • 1 investor on this round.
  5. Seed$600K2011-07-15
    • Filed alongside the prior round (same month) — likely a tranche or amendment.
    • Round 2.2× smaller than the prior — bridge or down round.
    • 4 investors on this round.
  6. Series B$21.0M2012-02-08
    • Came back fast: 7 mo vs the ~16 mo sector norm.
    • Round 35.0× larger than the prior — scaling up.
    • Revenue band moved $1M–$5M → $5M–$25M.
    • 17 investors on this round.
  7. Series B$3.0M2013-12-02
    • Raised 22 mo later, in step with the ~16 mo sector norm.
    • Round 7.0× smaller than the prior — bridge or down round.
    • Switched to Rule 506(b) (was Rule 06).
    • 10 investors on this round.
  8. Series B$7.5M2016-05-05
    • Raised again after 29 mo — slower than the ~16 mo sector norm.
    • Round 2.5× larger than the prior — scaling up.
    • 25 investors on this round.
  9. Series B$500K2018-05-28
    • Raised again after 25 mo — slower than the ~16 mo sector norm.
    • Round 15.0× smaller than the prior — bridge or down round.
    • 1 investor on this round.
  10. Series B$3.5M2022-04-29
    • Raised again after 47 mo — slower than the ~16 mo sector norm.
    • Round 7.1× larger than the prior — scaling up.
    • 26 investors on this round.
  11. Series B$408K2022-05-18
    • Came back fast: 1 mo vs the ~16 mo sector norm.
    • Round 8.7× smaller than the prior — bridge or down round.
    • 6 investors on this round.
  12. Series B$1.0M2023-08-01
    • Raised 14 mo later, in step with the ~16 mo sector norm.
    • Round 2.5× larger than the prior — scaling up.
    • 9 investors on this round.
  13. Series B$963K2023-12-19
    • Came back fast: 5 mo vs the ~16 mo sector norm.
    • Round roughly the size of the prior one.
    • 9 investors on this round.
  14. Series B$651K2024-05-20
    • Came back fast: 5 mo vs the ~16 mo sector norm.
    • Round 1.5× smaller than the prior — bridge or down round.
    • 11 investors on this round.
  15. Series B$849K2024-09-19
    • Came back fast: 4 mo vs the ~16 mo sector norm.
    • Round 1.3× larger than the prior — scaling up.
    • 10 investors on this round.
  16. Series B$791K2025-07-30
    • Raised 10 mo later, in step with the ~16 mo sector norm.
    • Round roughly the size of the prior one.
    • 9 investors on this round.
Intelligence
2026 ~Q3
Modeled next raise · ~12mo cadence
$791K
Modeled next size est.range $791K$1.3M
0.9×
Last step-up
$3.0M/yr
Capital velocity

Predictive signals are modeled est. from this company's own cadence and step-up, plus sector benchmarks — directional, not advice. Peer set and a CSV export live in your analyst workspace.

Key people & operators

Officers, directors and promoters named in this company's public recordsreported — the people who run it (not its investors). "Also runs" counts come from name-matching across all records, so verify before acting.

PersonRoleAlso runsTied since
C Eric Winzer3 other2010-04
David Jorden2 other2022-04
David E. Jorden1 other2010-04
JAMES S. BENSON1 other2010-04
Lawrence S. Atinsky1 other2018-05
Andrew P. Maslan2012-02
ANDREW S. MASLAN2010-04
BENSON S. JAMES2010-10
CRAIG B. MENDELSOHN2010-10
CRAIG B. MENDELSON2010-04
David P. Jorden2012-02
Eric C. Winzer2011-07
Eric P. Winzer2012-02
James P. Benson2012-02
Joseph E. Del Guercio2016-05
Joseph P. Del Guercio2012-02
KEITH N. STEPHEN2010-10
Lawrence Eric Atinsky2016-05
Lyle P. Hohnke2012-02
Mark P. McLoughlin2012-02
MARK T. MCLOUGHLIN2010-10
MARK T. MCLOUGHUN2010-04
MARTIN P. ROSENDALE2010-04
Patrick P. Vanek2011-07
Registry & provenance

Nuo Therapeutics, Inc. is an official record sourced from the U.S. Securities and Exchange Commission (SEC). U.S. data is aggregated from SEC Form D filings.

United States
Country of record
US
Jurisdiction
1091596
SEC CIK
Similar companies

Nearest neighbours across the whole database — matched on sector, stage and capital scale, and on shared operators (officers or directors named at both companies in public filings). A discovery shortlist, not a valuation cohort — verify before acting, the same way modeled figures are directional.

CompanySectorStageRaised · realValue · estWhy similar
EIP Pharma, Inc.PharmaSeries B$44.1M$8.3Msame sector · same stage
Multiply Labs, Inc.PharmaSeries B$41.2M$126.2Msame sector · same stage
Oncology Analytics, Inc.PharmaSeries B$53.5M$850.1Msame sector · same stage
Rescale, Inc.PharmaSeries B$58.2M$996.3Msame sector · same stage
Small Pharma Financing Inc.PharmaSeries B$35.1M$909.1Msame sector · same stage
Juvena Therapeutics, Inc.PharmaSeries B$34.8M$144.4Msame sector · same stage
Skincure Oncology LlcPharmaSeries B$33.5M$1.0Bsame sector · same stage
Pasithea Therapeutics Corp.PharmaSeries B$31.8M$591.3Msame sector · same stage
Semantically similar

Matched by meaning, not labels — a local language model reads each company's name, sector and description and ranks the closest in that learned space. This catches look-alikes that cross sector boundaries; the structured list above explains its matches, this one trusts the text. Directional, like every modeled signal here.

CompanySectorStageValue · estMatch
Nia Therapeutics, Inc.PharmaSeries B$357.8M87%
Levo Therapeutics, Inc.PharmaSeries C$1.4B85%
Pear Therapeutics, Inc.PharmaSeries D+$4.1B84%
Soleno Therapeutics IncPharmaSeries C$680.6M83%
Neela Therapeutics, Inc.PharmaSeries A$33.5M83%
Amani Therapeutics, Inc.PharmaSeries B$125.2M82%
Apie Therapeutics, Inc.PharmaPre-Seed$4.2M82%
Nula Therapeutics, Inc.BiotechnologySeries A$17.7M82%
Frequently asked
How much funding has Nuo Therapeutics, Inc. raised?
Nuo Therapeutics, Inc. has raised approximately $46.3M in disclosed capital across 16 recorded financing rounds, aggregated from public filings.
What is Nuo Therapeutics, Inc.'s estimated valuation?
Provath's modeled valuation for Nuo Therapeutics, Inc. is approximately $3.6M (modeled range $1.7M–$5.3M). This is an algorithmic estimate derived from round sizes and same-niche peers — not a quoted or reported figure.
What funding stage is Nuo Therapeutics, Inc. at?
Nuo Therapeutics, Inc.'s latest modeled financing stage is Series B. Its most recent recorded round closed around Wed Jul 30.
What does Nuo Therapeutics, Inc. do and where is it based?
Nuo Therapeutics, Inc. operates in the Pharma sector, based in Houston.
Explore related

See where Nuo Therapeutics, Inc. sits in the wider market — its sector, location and stage cohorts, each with their own leaderboards and capital-flow timelines.

Is this your company?

If you work at Nuo Therapeutics, Inc., claim this profile or suggest a correction. We aggregate from public filings, so help us keep your description, website and links accurate.

Is this your company? Update your profile or add contact details — and choose exactly who can reach you. Reviewed before anything is published.