Diligence memo · auto-generated · as of July 2, 2026

Metacrine, Inc.

Metacrine, Inc. looks fair against its niche peers and is dormant on financing cadence.

DeprioritizeFinancing has gone silent well past the sector's normal cadence — treat as inactive until outside confirmation of a live operation.

Businessfiled

Metacrine, Inc. operates in Pharmaceuticals, based in San Diego.

No verified homepage on file yet — operating evidence is limited to the public record.

Capital & rounds (filed)filed

Metacrine, Inc. has raised $125M in disclosed capital across 3 recorded rounds, aggregated from public filings. Its latest round is modeled as Series C (a $40M–$100M round).

Largest single filing: $65M on 2018-06-05.

Most recent recorded round closed around 2018-06-05.

Valuation (modeled)modeled

Provath models Metacrine, Inc. at approximately $2.3B (range $211M–$6.0B). This is an algorithmic estimate from round sizes and same-niche peers — not a quoted or reported figure.

Read: Fair. Modeled value is 0.98× the median modeled value of Series C Pharmaceuticals companies in 2016–2018 (32 peers) — value vs value, same stage and era. Within the normal band (98% of peer median) for its niche.

Financing rhythm & timingmixed

Historic cadence: a new round about every 10 months.

Last raise 8.1 yr ago; this sector typically re-raises about every 13 months.

Silent for over 3× the sector's normal cadence.

The last round stepped up 3.0× from the prior — scaling.

Comparablesmixed

Capital scale ranks ahead of 93% of Pharmaceuticals peers (1613 compared).

Modeled value ranks above 95% of those peers.

Closest niche peers: Amplyx Pharmaceuticals, Inc., Ligand Pharmaceuticals Inc, Homology Medicines, Inc., KSQ Therapeutics, Inc., TP Therapeutics, Inc..

Peoplefiled

12 named people on file across officers, directors and signatories.

Risks & flagsmixed

Financing has been silent well beyond sector cadence — possibly defunct, acquired, or paused.

No clearly named CEO/founder/principal in the surfaced records — key-person evidence is thin.