Diligence memo · auto-generated · as of July 2, 2026

Lygos, Inc.

Lygos, Inc. has raised $42M over 4 rounds; too few niche peers to rank its valuation yet.

DeprioritizeFinancing has gone silent well past the sector's normal cadence — treat as inactive until outside confirmation of a live operation.

Businessfiled

Lygos, Inc. operates in Biotech, based in BERKELEY, CA, USA. Lygos engineers yeast to convert sugar into high-value industrial…

Sub-sector tags: Biotechnology, Climate, Synthetic Biology, biotech, climate/cleantech.

Capital & rounds (filed)filed

Lygos, Inc. has raised $42M in disclosed capital across 4 recorded rounds, aggregated from public filings. Its latest round is modeled as Series B (a $15M–$40M round).

Largest single filing: $16M on 2018-03-13.

Most recent recorded round closed around 2018-11-09.

Valuation (modeled)modeled

Provath models Lygos, Inc. at approximately $433M (range $22M–$1.7B). This is an algorithmic estimate from round sizes and same-niche peers — not a quoted or reported figure.

Too few comparable companies in this niche to rank the valuation fairly yet.

Financing rhythm & timingmixed

Historic cadence: a new round about every 8 months.

Last raise 7.6 yr ago; this sector typically re-raises about every 11 months.

Silent for over 3× the sector's normal cadence.

The last round was 1.4× smaller than the prior — a bridge or down round.

Comparablesmixed

Capital scale ranks ahead of 97% of Biotech peers (233 compared).

Modeled value ranks above 98% of those peers.

Closest niche peers: Arix Bioscience plc, Yield10 Bioscience, Inc..

Peoplefiled

8 named people on file across officers, directors and signatories.

Risks & flagsmixed

Financing has been silent well beyond sector cadence — possibly defunct, acquired, or paused.

No clearly named CEO/founder/principal in the surfaced records — key-person evidence is thin.