Companies · Biotechnology

Cue Biopharma, Inc.

BOSTON · Biotechnology

Diligence memoA one-page analyst read on Cue Biopharma, Inc. — recommendation, valuation, rhythm, risks.
$57.4M
Total raised · real
4
Rounds
1.5×
Latest step-up
Top 17%
Sector rank · raised
Series B
Latest stage · inferred · Wed Nov 16 2022 00:00:00 GMT+0000 (Coordinated Universal Time)

Cue Biopharma, Inc. looks over-valued against its niche peers and is at-risk on financing cadence.

Synthesized from the figures below est. — every claim rests on a number shown on this page. Valuation uses the biotech sector profile.

Analyst read est. — computed against this company's niche peers in the same era. Inputs shown; not a quoted figure.

Over-valued
  • Modeled value is 2.56× the median modeled value of Series B Biotechnology companies in 2022–2024 (197 peers) — value vs value, same stage and era.
At-risk
  • Last raise 3.6 yr ago; this sector typically re-raises about every 14 months.
  • Past due for a raise versus sector cadence — watch for distress or a bridge.
Leadership

No named principal in this company's public records yet — see all operators below.

Explore how these operators interlock with other companies in the operator network.

Where it sits in Biotechnology

Cue Biopharma, Inc. is one of 4293 Biotechnology companies tracked from BOSTON. By capital raised it ranks in the upper tier (ahead of 84% of sector peers), and in the upper tier by modeled valuation est..

Ranking is computed against this company's own sector cohort — reported capital is fact; valuation tiers are modeled.

pharma

As reported in public records reported — not modeled.

US
Jurisdiction
Rule 506(b)
Reg D exemption
64
Investors (latest)
2022-11-16
First sale
Amount raised vs valuation, by round

Solid bars are reported offering amounts reported; hatched bars are the modeled post-money valuation est. — both on one shared scale so you can read raise-vs-worth at each round directly. Use the toggles to overlay data labels and the niche-peer / market average value lines.

Amount raised · realModeled valuation · estCumulative funded · real
$0$250M$500M$750M$1.0BPre-Seed · 2015-06-15 Raised $1.0M (real) Modeled valuation $55M (est)$1.0M$55MPre-Seed2015Series A · 2015-06-15 Raised $10M (real) Modeled valuation $362M (est)$10M$362MSeries A2015Series B · 2016-12-22 Raised $16M (real) Modeled valuation $651M (est)$16M$651MSeries B2016Series B · 2016-12-22 Raised $20M (real) Modeled valuation $794M (est)$20M$794MSeries B2016Series B · 2022-11-16 Raised $30M (real) Modeled valuation $430M (est)$30M$430MSeries B2022+$10M+$16M+$20M+$30MCumulative $77M

The line shows cumulative reported funding over the period; + labels show new capital added between points when there is room. Toggle on-bar figures, plus the niche-peer and market averages, to read this company against its cohort. Benchmarks are modeled medians.

Financing ladder & sequence gaps
Pre-Seed$1.0M · 2015
Series A$10.0M · 2015no Seed on file
Series B$16.4M · 2016
Series B extension$20.0M · 2016
Series B extension$30.0M · 2022

Stages are modeled from round size (public records carry no series label). No record for: Seed — the company may have raised it under a different exemption, merged it into an adjacent record, or skipped it. Sequence completeness: 75%.

Modeled valuation trajectory
$429.6M
Base estimate est.
$60.0M
Conservative case
$1.0B
Upside case
$166.7M
Modeled post-money

Round size and date are reported; the stage label is inferred from round size (latest is Series Ba $15M–$40M round). Valuation is modeled from stage benchmarks scaled by the biotech sector profile. Directional, not a quoted figure.

Pre-Seed · modeled $55.2M · 2015-06-152015Series A · modeled $361.5M · 2015-06-15Series B · modeled $651.5M · 2016-12-22Series B · modeled $793.8M · 2016-12-22Series B · modeled $429.6M · 2022-11-162022
Model inputs · modeled:benchmark-stage-stepup-v1
18%
Dilution assumption
Implied ownership sold in the financing.
54%
Survival probability
36% low · 66% high
1.54×/yr
Annual markup
1.86×/yr upside case
3.6 yr
Elapsed time used
3.6 yr actual, capped for stale marks
biotech
Sector profile
Adjusts growth and survival by industry.
Financing rhythm
22 mo
Avg between rounds
$7.7M/yr
Capital velocity
11.0 yr
On record since
2015
First round
5
Rounds on file
How it compares to the market

Benchmarked against 4293 companies in Biotechnology. Each bar is a median (the middle company, not an average — outliers don't skew it). Two yardsticks: real money raised (reported on Form D) and modeled value (our estimate est.). These are whole-sector medians across all stages, except the per-stage row.

Total raised — vs sector median (real $, all stages) 8.0× above median
This company$57.4M
Sector median$7.2M
Latest round — vs other Series B rounds in sector (real $, this stage) 1.7× above median
This company$30.0M
Sector median$17.5M
Modeled value — vs sector median (estimate, all stages) 6.7× above median
This company$429.6M
Sector median$64.2M

Raised more than 84% of sector peers (real $). Modeled value above 81% of peers (estimate).

Niche peers — same stage & era

A tighter cohort than the sector chart above — only companies at the same stage (Series B) that last raised in the same ~3-year era, ranked by modeled value est. (not money raised). This is the exact set the analyst read compares against, so a like-for-like cohort is what makes "over/under-valued" meaningful. This company ranks #23 of 197.

This companyCohort peer
$100.0M$1.0B$10.0M$100.0M$1.0BCapital raised (log)Mt McKinley Medical Holding Corp USA · Series B Raised $40.0M · modeled $738.4M (est)YAP Therapeutics Inc · Series B Raised $30.1M · modeled $618.3M (est)Pinteon Therapeutics, Inc. · Series B Raised $39.2M · modeled $603.8M (est)OncXerna Therapeutics, Ltd. · Series B Raised $30.0M · modeled $591.4M (est)EpiBiologics, Inc. · Series B Raised $30.0M · modeled $570.2M (est)GIOGI Ltd · Series B Raised $27.3M · modeled $554.5M (est)SonoThera, Inc. · Series B Raised $30.4M · modeled $550.9M (est)Perceive Biotherapeutics, Inc. · Series B Raised $40.0M · modeled $544.6M (est)GIOCAN Ltd · Series B Raised $24.5M · modeled $498.6M (est)GIODIA Ltd · Series B Raised $24.5M · modeled $498.6M (est)GIOHEALTH Ltd · Series B Raised $24.5M · modeled $498.6M (est)Cerapedics Inc · Series B Raised $99.1M · modeled $492.3M (est)Cue Biopharma, Inc. (this company) Raised $57.4M · modeled $429.6M (est)Cue Biopharma, Inc.
CompanyStageRaised · realValue · estvs peer med.
Mt McKinley Medical Holding Corp USASeries B$40.0M$738.4M4.41×
YAP Therapeutics IncSeries B$30.1M$618.3M3.69×
Pinteon Therapeutics, Inc.Series B$39.2M$603.8M3.60×
OncXerna Therapeutics, Ltd.Series B$30.0M$591.4M3.53×
EpiBiologics, Inc.Series B$30.0M$570.2M3.40×
GIOGI LtdSeries B$27.3M$554.5M3.31×
SonoThera, Inc.Series B$30.4M$550.9M3.29×
Perceive Biotherapeutics, Inc.Series B$40.0M$544.6M3.25×
GIOCAN LtdSeries B$24.5M$498.6M2.97×
GIODIA LtdSeries B$24.5M$498.6M2.97×
GIOHEALTH LtdSeries B$24.5M$498.6M2.97×
Cerapedics IncSeries B$99.1M$492.3M2.94×
Cue Biopharma, Inc. this companySeries B$57.4M$429.6M2.56×
Full financing history

Stage is inferred from round size est., not reported on the filing — a round's dollar size maps to a bucket: Pre-Seed <$1.0M · Seed $1.0M–$4.0M · Series A $4.0M–$15M · Series B $15M–$40M · Series C $40M–$100M · Series D+ $100M–$400M · Growth/Late >$400M.

StageAmount · realAnnouncedPost-money · estValue · estConf.
Pre-Seed$1.0M2015-06-15$5.6M$55.2M85%
Series A$10.0M2015-06-15$45.5M$361.5M85%
Series B$16.4M2016-12-22$91.2M$651.5M90%
Series B$20.0M2016-12-22$111.1M$793.8M90%
Series B$30.0M2022-11-16$166.7M$429.6M90%
What happened at each round

Step-up, pace versus the sector's normal cadence, and revenue/exemption moves — read straight from the reported round facts reported.

  1. Pre-Seed$1.0M2015-06-15
    • First recorded raise — entered as Pre-Seed.
    • 1 investor on this round.
  2. Series A$10.0M2015-06-15
    • Filed alongside the prior round (same month) — likely a tranche or amendment.
    • Round 10.0× larger than the prior — scaling up.
    • 121 investors on this round.
  3. Series B$16.4M2016-12-22
    • Raised 18 mo later, in step with the ~14 mo sector norm.
    • Round 1.6× larger than the prior — scaling up.
    • 133 investors on this round.
  4. Series B$20.0M2016-12-22
    • Filed alongside the prior round (same month) — likely a tranche or amendment.
    • Round roughly the size of the prior one.
    • 133 investors on this round.
  5. Series B$30.0M2022-11-16
    • Raised again after 71 mo — slower than the ~14 mo sector norm.
    • Round 1.5× larger than the prior — scaling up.
    • 64 investors on this round.
Intelligence
2024 ~Q3
Modeled next raise · ~22mo cadence
$45.0M
Modeled next size est.range $30.0M$72.0M
1.5×
Last step-up
$7.7M/yr
Capital velocity

Predictive signals are modeled est. from this company's own cadence and step-up, plus sector benchmarks — directional, not advice. Peer set and a CSV export live in your analyst workspace.

Key people & operators

Officers, directors and promoters named in this company's public recordsreported — the people who run it (not its investors). "Also runs" counts come from name-matching across all records, so verify before acting.

PersonRoleAlso runsTied since
Amy Wang4 other2015-06
Cameron Gray3 other2015-06
Peter Kiener3 other2016-12
Anthony DiGiandomenico2 other2015-06
Barry Simon2 other2016-12
Christopher Marlett2 other2015-06
Peter A. Kiener2 other2022-11
Daniel R. Passeri1 other2022-11
Gary Schuman1 other2015-06
Aaron G. Fletcher2022-11
Anish R. Suri2022-11
Colin G. Sandercock2022-11
DANIEL PASSERI2016-12
Frank G. Morich2022-11
Frederick G. Driscoll2022-11
Ken R. Pienta2022-11
Kerri-Ann R. Millar2022-11
Patricia R. Nasshorn2022-11
Rodolfo Chaparro2015-06
Ronald Seidel III2015-06
Steven Almo2015-06
STEVEN MCKNIGHT2016-12
Tamar G. Howson2022-11
Registry & provenance

Cue Biopharma, Inc. is an official record sourced from the U.S. Securities and Exchange Commission (SEC). U.S. data is aggregated from SEC Form D filings.

United States
Country of record
US
Jurisdiction
1645460
SEC CIK
Similar companies

Nearest neighbours across the whole database — matched on sector, stage and capital scale, and on shared operators (officers or directors named at both companies in public filings). A discovery shortlist, not a valuation cohort — verify before acting, the same way modeled figures are directional.

CompanySectorStageRaised · realValue · estWhy similar
Provention Bio, Inc.BiotechnologySeries B$28.5M$1.1Bnetwork2 shared operators · same sector · same stage
iTolerance, Inc.BiotechnologySeries B$17.2M$424.0Mnetwork2 shared operators · same sector · same stage
Pulse Biosciences, Inc.BiotechnologySeries C$93.0M$1.4Bnetwork2 shared operators · same sector
theMaven, Inc.Other TechnologySeries B$128.2M$440.1Mnetwork2 shared operators · same stage
AmpliPhi Biosciences CorpBiotechnologySeries B$57.3M$516.0Msame sector · same stage
NanoCellect Biomedical, Inc.BiotechnologySeries B$58.6M$322.9Msame sector · same stage
Human Longevity, Inc.BiotechnologySeries B$59.0M$399.4Msame sector · same stage
WaferGen Bio-systems, Inc.BiotechnologySeries B$59.7M$542.5Msame sector · same stage
Semantically similar

Matched by meaning, not labels — a local language model reads each company's name, sector and description and ranks the closest in that learned space. This catches look-alikes that cross sector boundaries; the structured list above explains its matches, this one trusts the text. Directional, like every modeled signal here.

CompanySectorStageValue · estMatch
National Biopharma, LLCBiotechnologySeed$88.8M82%
LogicBio Therapeutics, Inc.BiotechnologySeries B$1.2B82%
Principia Biopharma Inc.BiotechnologySeries C$2.0B80%
Vitro Biopharma, Inc.BiotechnologySeed$294K80%
Neuropharma, Inc.BiotechnologySeed$74.1M80%
Gain Therapeutics, Inc.BiotechnologySeries A$352.8M80%
Flow Pharma, Inc.BiotechnologySeed$1.0M79%
Benitec Biopharma Inc.BiotechnologySeries C$383.9M79%
Frequently asked
How much funding has Cue Biopharma, Inc. raised?
Cue Biopharma, Inc. has raised approximately $57.4M in disclosed capital across 4 recorded financing rounds, aggregated from public filings.
What is Cue Biopharma, Inc.'s estimated valuation?
Provath's modeled valuation for Cue Biopharma, Inc. is approximately $429.6M (modeled range $60.0M–$1.0B). This is an algorithmic estimate derived from round sizes and same-niche peers — not a quoted or reported figure.
What funding stage is Cue Biopharma, Inc. at?
Cue Biopharma, Inc.'s latest modeled financing stage is Series B. Its most recent recorded round closed around Wed Nov 16.
What does Cue Biopharma, Inc. do and where is it based?
Cue Biopharma, Inc. operates in the Biotechnology sector, based in BOSTON.
Explore related

See where Cue Biopharma, Inc. sits in the wider market — its sector, location and stage cohorts, each with their own leaderboards and capital-flow timelines.

Is this your company?

If you work at Cue Biopharma, Inc., claim this profile or suggest a correction. We aggregate from public filings, so help us keep your description, website and links accurate.

Is this your company? Update your profile or add contact details — and choose exactly who can reach you. Reviewed before anything is published.