Companies · Biotechnology
San Francisco · MO, USA · Biotechnology · founded 2015 · http://cofactorgenomics.com
Diligence memoA one-page analyst read on Cofactor Genomics, Inc. — recommendation, valuation, rhythm, risks.→Cofactor Genomics, Inc. looks under-valued against its niche peers and is at-risk on financing cadence.
Synthesized from the figures below est. — every claim rests on a number shown on this page. Valuation uses the biotech sector profile.
Analyst read est. — computed against this company's niche peers in the same era. Inputs shown; not a quoted figure.
No named principal in this company's public records yet — see all operators below.
Explore how these operators interlock with other companies in the operator network.
Cofactor Genomics, Inc. is one of 4291 Biotechnology companies tracked from San Francisco, MO, USA, on record since 2015. By capital raised it ranks mid-pack (ahead of 67% of sector peers), and in the long tail by modeled valuation est..
Ranking is computed against this company's own sector cohort — reported capital is fact; valuation tiers are modeled.
AI analyst read est. — model-extracted from this company's public description, not a verified fact. 30%
operates a technology-led product inferred from public copy
Grounded in: “You are a venture analyst”
Cofactor closes the precision medicine gap with predictive diagnostics
Cofactor uses RNA and Predictive Immune Modeling to build better biomarkers and improve patient outcomes. Led by Jarret Glasscock and a group of expert human genome scientists,Cofactor has built a new category of diagnostic technology powered by unique and powerful RNA data models built on terabytes of data. The team recently had their technology validation peer-reviewed by the organizations that set standards for diagnostic technology (CAP, AMP) and is publishing in the Journal of Molecular Diagnostics. In addition, the team made news when Cancer Physicians who sit on the committee for patient treatment guidelines (NCCN) presented a clinical study using Cofactor’s technology showing superiority in predicting the patients who will respond to immunotherapy. This initial application is an acute problem recognized widely in the rapidly developing immunotherapy industry and represents north of a billion dollar TAM. After a number of recent key milestones, the team is taking the technology more broadly to 50% of cancers diagnosed in the US. Current investors include Menlo Ventures, DCVC, and Ascension Ventures (this last investor representing the funding arm for 13 National U.S. Healthcare Systems).
As reported in public records reported — not modeled.
Solid bars are reported offering amounts reported; hatched bars are the modeled post-money valuation est. — both on one shared scale so you can read raise-vs-worth at each round directly. Use the toggles to overlay data labels and the niche-peer / market average value lines.
The line shows cumulative reported funding over the period; + labels show new capital added between points when there is room. Toggle on-bar figures, plus the niche-peer and market averages, to read this company against its cohort. Benchmarks are modeled medians.
Stages are modeled from round size (public records carry no series label). No record for: Pre-Seed, Seed — the company may have raised it under a different exemption, merged it into an adjacent record, or skipped it. Sequence completeness: 33%.
Round size and date are reported; the stage label is inferred from round size (latest is Series A — a $4.0M–$15M round). Valuation is modeled from stage benchmarks scaled by the biotech sector profile. Directional, not a quoted figure.
Benchmarked against 4291 companies in Biotechnology. Each bar is a median (the middle company, not an average — outliers don't skew it). Two yardsticks: real money raised (reported on Form D) and modeled value (our estimate est.). These are whole-sector medians across all stages, except the per-stage row.
Raised more than 67% of sector peers (real $). Modeled value above 18% of peers (estimate).
A tighter cohort than the sector chart above — only companies at the same stage (Series A) that last raised in the same ~3-year era, ranked by modeled value est. (not money raised). This is the exact set the analyst read compares against, so a like-for-like cohort is what makes "over/under-valued" meaningful. This company ranks #264 of 303.
| Company | Stage | Raised · real | Value · est | vs peer med. |
|---|---|---|---|---|
| GeoVax Labs, Inc. | Series A | $39.1M | $217.0M | 4.90× |
| Cellinfinity Bio Holding Company, LLC | Series A | $13.2M | $215.9M | 4.87× |
| Adient Medical, Inc. | Series A | $18.2M | $206.8M | 4.67× |
| Entegrion Inc | Series A | $22.7M | $191.3M | 4.32× |
| BCD Bioscience, Inc. | Series A | $16.4M | $188.9M | 4.27× |
| Pragma Biosciences Inc. | Series A | $14.5M | $186.0M | 4.20× |
| MicroByre, Inc. | Series A | $16.1M | $185.7M | 4.19× |
| Cardiac Insight, Inc. | Series A | $38.1M | $183.8M | 4.15× |
| Cardiac Implants LLC | Series A | $13.5M | $178.2M | 4.02× |
| Abintus Bio, Inc. | Series A | $13.7M | $177.2M | 4.00× |
| Mosaic Biosciences, Inc. | Series A | $14.7M | $176.1M | 3.98× |
| Mazen Animal Health Inc. | Series A | $13.5M | $168.8M | 3.81× |
| Cofactor Genomics, Inc. this company | Series A | $18.8M | $9.7M | 0.22× |
Stage is inferred from round size est., not reported on the filing — a round's dollar size maps to a bucket: Pre-Seed <$1.0M · Seed $1.0M–$4.0M · Series A $4.0M–$15M · Series B $15M–$40M · Series C $40M–$100M · Series D+ $100M–$400M · Growth/Late >$400M.
| Stage | Amount · real | Announced | Post-money · est | Value · est | Conf. |
|---|---|---|---|---|---|
| Series A | $10.7M | 2017-06-14 | $48.6M | $386.2M | 90% |
| Series A | $6.9M | 2021-12-08 | $31.4M | $124.7M | 90% |
| Series A | $1.2M | 2023-07-20 | $5.3M | $9.7M | 90% |
Step-up, pace versus the sector's normal cadence, and revenue/exemption moves — read straight from the reported round facts reported.
Predictive signals are modeled est. from this company's own cadence and step-up, plus sector benchmarks — directional, not advice. Peer set and a CSV export live in your analyst workspace.
Officers, directors and promoters named in this company's public recordsreported — the people who run it (not its investors). "Also runs" counts come from name-matching across all records, so verify before acting.
| Person | Role | Also runs | Tied since |
|---|---|---|---|
| Mark Siegel | — | 7 other | 2017-06 |
| John Kuelper | — | 5 other | 2021-12 |
| Armen Vidian | — | 4 other | 2021-12 |
| William Hagstrom | — | 3 other | 2021-12 |
| Jon Armstrong | — | 1 other | 2017-06 |
| David Messina | — | — | 2021-12 |
| Jarret Glasscock | — | — | 2021-12 |
| Jarret Glassock | — | — | 2017-06 |
| Matthew A. Ocko | — | — | 2017-06 |
Cofactor Genomics, Inc. is an official record sourced from the U.S. Securities and Exchange Commission (SEC). U.S. data is aggregated from SEC Form D filings.
Nearest neighbours across the whole database — matched on sector, stage and capital scale, and on shared operators (officers or directors named at both companies in public filings). A discovery shortlist, not a valuation cohort — verify before acting, the same way modeled figures are directional.
| Company | Sector | Stage | Raised · real | Value · est | Why similar |
|---|---|---|---|---|---|
| Bluestem Biosciences, Inc. | Biotechnology | Series A | $5.0M | $68.2M | network1 shared operator · same sector · same stage |
| PhAST Corp. | Biotechnology | Series A | $18.6M | $12.5M | same sector · same stage |
| Hdl Therapeutics, Inc. | Biotechnology | Series A | $17.8M | $10.9M | same sector · same stage |
| GeneCentric Therapeutics, Inc. | Biotechnology | Series A | $21.6M | $6.7M | same sector · same stage |
| Plasmology4, Inc. | Biotechnology | Series A | $16.2M | $9.0M | same sector · same stage |
| Cadrenal Therapeutics, Inc. | Biotechnology | Series A | $21.7M | $11.4M | same sector · same stage |
| InGeneron, Inc. | Biotechnology | Series A | $21.8M | $11.0M | same sector · same stage |
| Model Medicines, Inc. | Biotechnology | Series A | $22.5M | $9.0M | same sector · same stage |
Matched by meaning, not labels — a local language model reads each company's name, sector and description and ranks the closest in that learned space. This catches look-alikes that cross sector boundaries; the structured list above explains its matches, this one trusts the text. Directional, like every modeled signal here.
| Company | Sector | Stage | Value · est | Match |
|---|---|---|---|---|
| PostEra Inc. Medicinal Chemistry powered by Machine Learning | Biotechnology | Series B | $542.8M | 76% |
| Blank Bio RNA intelligence for precision medicine | Biotech | — | — | 75% |
| Co-Diagnostics, Inc. | Biotechnology | Series C | $1.1B | 75% |
| CoFlo Medical, Inc. | Biotechnology | Pre-Seed | $999K | 75% |
| Cognigenics, Inc. | Biotechnology | Seed | $23.9M | 75% |
| Helix Nanotechnologies Next-generation mRNA platform to solve cancer, COVID and climate. | Biotech | — | — | 75% |
| Genomic Prediction, Inc. | Biotech / Pharma | Series A | $211.6M | 75% |
| Cambridge Cancer Genomics CCG.ai empowers clinicians to make personalised treatment strategies… | Biotech | — | — | 75% |
See where Cofactor Genomics, Inc. sits in the wider market — its sector, location and stage cohorts, each with their own leaderboards and capital-flow timelines.
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