Companies · Biotechnology

Cleave Biosciences, Inc.

BURLINGAME · Biotechnology

Diligence memoA one-page analyst read on Cleave Biosciences, Inc. — recommendation, valuation, rhythm, risks.
$37.9M
Total raised · real
2
Rounds
0.5×
Latest step-up
Top 23%
Sector rank · raised
Series B
Latest stage · inferred · Tue Jun 04 2019 00:00:00 GMT+0000 (Coordinated Universal Time)

Cleave Biosciences, Inc. looks fair against its niche peers and is dormant on financing cadence.

Synthesized from the figures below est. — every claim rests on a number shown on this page. Valuation uses the biotech sector profile.

Analyst read est. — computed against this company's niche peers in the same era. Inputs shown; not a quoted figure.

Fair
  • Modeled value is 0.77× the median modeled value of Series B Biotechnology companies in 2019–2021 (118 peers) — value vs value, same stage and era.
  • Within the normal band (77% of peer median) for its niche.
Dormant
  • Last raise 7.1 yr ago; this sector typically re-raises about every 14 months.
  • Silent for over 3× the sector's normal cadence.
Leadership

No named principal in this company's public records yet — see all operators below.

Explore how these operators interlock with other companies in the operator network.

Where it sits in Biotechnology

Cleave Biosciences, Inc. is one of 4293 Biotechnology companies tracked from BURLINGAME. By capital raised it ranks in the upper tier (ahead of 78% of sector peers), and in the upper tier by modeled valuation est..

Ranking is computed against this company's own sector cohort — reported capital is fact; valuation tiers are modeled.

As reported in public records reported — not modeled.

US
Jurisdiction
Rule 506(b)
Reg D exemption
11
Investors (latest)
2019-06-04
First sale
Amount raised vs valuation, by round

Solid bars are reported offering amounts reported; hatched bars are the modeled post-money valuation est. — both on one shared scale so you can read raise-vs-worth at each round directly. Use the toggles to overlay data labels and the niche-peer / market average value lines.

Amount raised · realModeled valuation · estCumulative funded · real
$0$500M$1.0B$1.5B$2.0BSeries B · 2016-06-16 Raised $26M (real) Modeled valuation $1.0B (est)$26M$1.0BSeries B2016Series B · 2019-06-04 Raised $12M (real) Modeled valuation $475M (est)$12M$475MSeries B2019+$12MCumulative $38M

The line shows cumulative reported funding over the period; + labels show new capital added between points when there is room. Toggle on-bar figures, plus the niche-peer and market averages, to read this company against its cohort. Benchmarks are modeled medians.

Financing ladder & sequence gaps
Series B$26.0M · 2016
Series B extension$12.0M · 2019

Stages are modeled from round size (public records carry no series label). No record for: Pre-Seed, Seed, Series A — the company may have raised it under a different exemption, merged it into an adjacent record, or skipped it. Sequence completeness: 25%.

Modeled valuation trajectory
$475.1M
Base estimate est.
$23.9M
Conservative case
$1.8B
Upside case
$66.5M
Modeled post-money

Round size and date are reported; the stage label is inferred from round size (latest is Series Ba $15M–$40M round). Valuation is modeled from stage benchmarks scaled by the biotech sector profile. Directional, not a quoted figure.

Series B · modeled $1.0B · 2016-06-162016Series B · modeled $475.1M · 2019-06-042019
Model inputs · modeled:benchmark-stage-stepup-v1
18%
Dilution assumption
Implied ownership sold in the financing.
54%
Survival probability
36% low · 66% high
1.54×/yr
Annual markup
1.86×/yr upside case
6.0 yr
Elapsed time used
7.1 yr actual, capped for stale marks
biotech
Sector profile
Adjusts growth and survival by industry.
Financing rhythm
36 mo
Avg between rounds
$12.8M/yr
Capital velocity
10.0 yr
On record since
2016
First round
2
Rounds on file
How it compares to the market

Benchmarked against 4293 companies in Biotechnology. Each bar is a median (the middle company, not an average — outliers don't skew it). Two yardsticks: real money raised (reported on Form D) and modeled value (our estimate est.). These are whole-sector medians across all stages, except the per-stage row.

Total raised — vs sector median (real $, all stages) 5.3× above median
This company$37.9M
Sector median$7.2M
Latest round — vs other Series B rounds in sector (real $, this stage) 0.7× of median
This company$12.0M
Sector median$17.5M
Modeled value — vs sector median (estimate, all stages) 7.4× above median
This company$475.1M
Sector median$64.2M

Raised more than 78% of sector peers (real $). Modeled value above 82% of peers (estimate).

Niche peers — same stage & era

A tighter cohort than the sector chart above — only companies at the same stage (Series B) that last raised in the same ~3-year era, ranked by modeled value est. (not money raised). This is the exact set the analyst read compares against, so a like-for-like cohort is what makes "over/under-valued" meaningful. This company ranks #80 of 118.

This companyCohort peer
$100.0M$1.0B$10.0B$10.0M$100.0M$1.0BCapital raised (log)Pandion Therapeutics Holdco LLC · Series B Raised $40.0M · modeled $1.6B (est)Ocular Therapeutix, Inc · Series B Raised $81.0M · modeled $1.5B (est)Insilico Medicine Cayman TopCo · Series B Raised $36.8M · modeled $1.5B (est)Purigen Biosystems, Inc. · Series B Raised $61.9M · modeled $1.4B (est)Lucira Health, Inc. · Series B Raised $32.5M · modeled $1.3B (est)Peptilogics, Inc. · Series B Raised $40.9M · modeled $1.2B (est)Nanotech Energy, Inc. · Series B Raised $31.6M · modeled $1.1B (est)Windtree Therapeutics Inc /De/ · Series B Raised $104.5M · modeled $1.0B (est)Liminal BioSciences Inc. · Series B Raised $67.1M · modeled $1.0B (est)Palladio Biosciences, Inc. · Series B Raised $28.0M · modeled $1.0B (est)Faze Medicines, Inc. · Series B Raised $30.4M · modeled $999.5M (est)Inivata Ltd · Series B Raised $25.0M · modeled $992.2M (est)Cleave Biosciences, Inc. (this company) Raised $37.9M · modeled $475.1M (est)Cleave Biosciences, Inc.
CompanyStageRaised · realValue · estvs peer med.
Pandion Therapeutics Holdco LLCSeries B$40.0M$1.6B2.58×
Ocular Therapeutix, IncSeries B$81.0M$1.5B2.42×
Insilico Medicine Cayman TopCoSeries B$36.8M$1.5B2.37×
Purigen Biosystems, Inc.Series B$61.9M$1.4B2.22×
Lucira Health, Inc.Series B$32.5M$1.3B2.10×
Peptilogics, Inc.Series B$40.9M$1.2B1.90×
Nanotech Energy, Inc.Series B$31.6M$1.1B1.82×
Windtree Therapeutics Inc /De/Series B$104.5M$1.0B1.70×
Liminal BioSciences Inc.Series B$67.1M$1.0B1.67×
Palladio Biosciences, Inc.Series B$28.0M$1.0B1.63×
Faze Medicines, Inc.Series B$30.4M$999.5M1.62×
Inivata LtdSeries B$25.0M$992.2M1.61×
Cleave Biosciences, Inc. this companySeries B$37.9M$475.1M0.77×
Full financing history

Stage is inferred from round size est., not reported on the filing — a round's dollar size maps to a bucket: Pre-Seed <$1.0M · Seed $1.0M–$4.0M · Series A $4.0M–$15M · Series B $15M–$40M · Series C $40M–$100M · Series D+ $100M–$400M · Growth/Late >$400M.

StageAmount · realAnnouncedPost-money · estValue · estConf.
Series B$26.0M2016-06-16$144.2M$1.0B85%
Series B$12.0M2019-06-04$66.5M$475.1M90%
What happened at each round

Step-up, pace versus the sector's normal cadence, and revenue/exemption moves — read straight from the reported round facts reported.

  1. Series B$26.0M2016-06-16
    • First recorded raise — entered as Series B.
    • 13 investors on this round.
  2. Series B$12.0M2019-06-04
    • Raised again after 36 mo — slower than the ~14 mo sector norm.
    • Round 2.2× smaller than the prior — bridge or down round.
    • 11 investors on this round.
Intelligence
2022 ~Q2
Modeled next raise · ~36mo cadence
$12.0M
Modeled next size est.range $12.0M$19.2M
0.5×
Last step-up
$12.8M/yr
Capital velocity

Predictive signals are modeled est. from this company's own cadence and step-up, plus sector benchmarks — directional, not advice. Peer set and a CSV export live in your analyst workspace.

Key people & operators

Officers, directors and promoters named in this company's public recordsreported — the people who run it (not its investors). "Also runs" counts come from name-matching across all records, so verify before acting.

PersonRoleAlso runsTied since
Andrew Schwab15 other2016-06
Jonathan Root15 other2016-06
Peter Thompson15 other2016-06
Carol Gallagher5 other2016-06
Laura Shawver5 other2016-06
DENNIS HENNER4 other2016-06
Timothy Smith4 other2016-06
Lewis Shuster1 other2016-06
Alfred Scheidegger2016-06
Amy Burroughs2019-06
Mark Rolfe2016-06
Registry & provenance

Cleave Biosciences, Inc. is an official record sourced from the U.S. Securities and Exchange Commission (SEC). U.S. data is aggregated from SEC Form D filings.

United States
Country of record
US
Jurisdiction
1682401
SEC CIK
Similar companies

Nearest neighbours across the whole database — matched on sector, stage and capital scale, and on shared operators (officers or directors named at both companies in public filings). A discovery shortlist, not a valuation cohort — verify before acting, the same way modeled figures are directional.

CompanySectorStageRaised · realValue · estWhy similar
Synthorx, Inc.BiotechnologySeries B$34.7M$1.1Bnetwork2 shared operators · same sector · same stage
Silverback Therapeutics, Inc.BiotechnologySeries C$139.3M$3.2Bnetwork3 shared operators · same sector
Flexion Therapeutics IncBiotechnologySeries B$40.0M$793.8Mnetwork1 shared operator · same sector · same stage
Gennao Bio, Inc.BiotechnologySeries B$47.5M$211.8Mnetwork1 shared operator · same sector · same stage
Ocunexus Therapeutics, Inc.BiotechnologySeries B$53.2M$292.6Mnetwork1 shared operator · same sector · same stage
Purigen Biosystems, Inc.BiotechnologySeries B$61.9M$1.4Bnetwork1 shared operator · same sector · same stage
Edgewise Therapeutics, Inc.BiotechnologySeries C$120.1M$3.3Bnetwork2 shared operators · same sector
Ribon Therapeutics, Inc.BiotechnologySeries B$119.1M$343.2Mnetwork1 shared operator · same sector · same stage
Semantically similar

Matched by meaning, not labels — a local language model reads each company's name, sector and description and ranks the closest in that learned space. This catches look-alikes that cross sector boundaries; the structured list above explains its matches, this one trusts the text. Directional, like every modeled signal here.

CompanySectorStageValue · estMatch
Florey Biosciences, Inc.BiotechnologySeed$4.4M89%
SiVEC Biotechnologies, Inc.BiotechnologySeed$8.4M89%
Claris Biotherapeutics, Inc.BiotechnologySeries C$13.0M89%
Creatus Biosciences Inc.BiotechnologyPre-Seed$12.0M88%
Clerio Vision Inc.BiotechnologySeries A$242.3M87%
BioCurie, Inc.BiotechnologyPre-Seed$1.3M87%
Biosceptre International LtdBiotechnologyPre-Seed$13.1M87%
CIRC Biosciences, Inc.BiotechnologySeries B$54.7M87%
Frequently asked
How much funding has Cleave Biosciences, Inc. raised?
Cleave Biosciences, Inc. has raised approximately $37.9M in disclosed capital across 2 recorded financing rounds, aggregated from public filings.
What is Cleave Biosciences, Inc.'s estimated valuation?
Provath's modeled valuation for Cleave Biosciences, Inc. is approximately $475.1M (modeled range $23.9M–$1.8B). This is an algorithmic estimate derived from round sizes and same-niche peers — not a quoted or reported figure.
What funding stage is Cleave Biosciences, Inc. at?
Cleave Biosciences, Inc.'s latest modeled financing stage is Series B. Its most recent recorded round closed around Tue Jun 04.
What does Cleave Biosciences, Inc. do and where is it based?
Cleave Biosciences, Inc. operates in the Biotechnology sector, based in BURLINGAME.
Explore related

See where Cleave Biosciences, Inc. sits in the wider market — its sector, location and stage cohorts, each with their own leaderboards and capital-flow timelines.

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