Companies · Biotechnology

Avenzo Therapeutics, Inc.

SAN DIEGO · Biotechnology

Diligence memoA one-page analyst read on Avenzo Therapeutics, Inc. — recommendation, valuation, rhythm, risks.
$270.6M
Total raised · real
2
Rounds
0.2×
Latest step-up
Top 3%
Sector rank · raised
Series D+
Latest stage · inferred · Fri Aug 22 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

Avenzo Therapeutics, Inc. looks under-valued against its niche peers and is active on financing cadence.

Synthesized from the figures below est. — every claim rests on a number shown on this page. Valuation uses the biotech sector profile.

Analyst read est. — computed against this company's niche peers in the same era. Inputs shown; not a quoted figure.

Under-valued
  • Modeled value is 0.40× the median modeled value of Series D+ Biotechnology companies in 2025–2027 (33 peers) — value vs value, same stage and era.
Active
  • Last raise 10 mo ago; this sector typically re-raises about every 14 months.
  • Raising on or ahead of the sector's normal rhythm.
Leadership

No named principal in this company's public records yet — see all operators below.

Explore how these operators interlock with other companies in the operator network.

Where it sits in Biotechnology

Avenzo Therapeutics, Inc. is one of 4293 Biotechnology companies tracked from SAN DIEGO. By capital raised it ranks among the largest (ahead of 98% of sector peers), and in the upper tier by modeled valuation est..

Ranking is computed against this company's own sector cohort — reported capital is fact; valuation tiers are modeled.

pharma

As reported in public records reported — not modeled.

US
Jurisdiction
Rule 506(b)
Reg D exemption
20
Investors (latest)
2022
Year incorporated
2025-08-22
First sale
Amount raised vs valuation, by round

Solid bars are reported offering amounts reported; hatched bars are the modeled post-money valuation est. — both on one shared scale so you can read raise-vs-worth at each round directly. Use the toggles to overlay data labels and the niche-peer / market average value lines.

Amount raised · realModeled valuation · estCumulative funded · real
$0$2.5B$5.0B$7.5B$10.0BSeries B · 2022-09-14 Raised $31M (real) Modeled valuation $486M (est)$31M$486MSeries B2022Series D+ · 2022-09-14 Raised $386M (real) Modeled valuation $7.7B (est)$386M$7.7BSeries D+2022Series D+ · 2022-09-14 Raised $223M (real) Modeled valuation $4.4B (est)$223M$4.4BSeries D+2022Series D+ · 2025-08-22 Raised $47M (real) Modeled valuation $356M (est)$47M$356MSeries D+2025+$386M+$223M+$47MCumulative $688M

The line shows cumulative reported funding over the period; + labels show new capital added between points when there is room. Toggle on-bar figures, plus the niche-peer and market averages, to read this company against its cohort. Benchmarks are modeled medians.

Financing ladder & sequence gaps
Series B$31.5M · 2022
Series D+$385.9M · 2022no Series C on file
Series D+ extension$223.4M · 2022
Series D+ extension$47.2M · 2025

Stages are modeled from round size (public records carry no series label). No record for: Pre-Seed, Seed, Series A, Series C — the company may have raised it under a different exemption, merged it into an adjacent record, or skipped it. Sequence completeness: 33%.

Modeled valuation trajectory
$355.7M
Base estimate est.
$214.1M
Conservative case
$433.8M
Upside case
$393.6M
Modeled post-money

Round size and date are reported; the stage label is inferred from round size (latest is Series D+a $100M–$400M round). Valuation is modeled from stage benchmarks scaled by the biotech sector profile. Directional, not a quoted figure.

Series B · modeled $485.8M · 2022-09-142022Series D+ · modeled $7.7B · 2022-09-14Series D+ · modeled $4.4B · 2022-09-14Series D+ · modeled $355.7M · 2025-08-222025
Model inputs · modeled:benchmark-stage-stepup-v1
12%
Dilution assumption
Implied ownership sold in the financing.
68%
Survival probability
54% low · 75% high
1.39×/yr
Annual markup
1.56×/yr upside case
0.9 yr
Elapsed time used
0.9 yr actual, capped for stale marks
biotech
Sector profile
Adjusts growth and survival by industry.
Financing rhythm
12 mo
Avg between rounds
$92.1M/yr
Capital velocity
3.8 yr
On record since
2022
First round
4
Rounds on file
How it compares to the market

Benchmarked against 4293 companies in Biotechnology. Each bar is a median (the middle company, not an average — outliers don't skew it). Two yardsticks: real money raised (reported on Form D) and modeled value (our estimate est.). These are whole-sector medians across all stages, except the per-stage row.

Total raised — vs sector median (real $, all stages) 38× above median
This company$270.6M
Sector median$7.2M
Latest round — vs other Series D+ rounds in sector (real $, this stage) 0.4× of median
This company$47.2M
Sector median$120.0M
Modeled value — vs sector median (estimate, all stages) 5.5× above median
This company$355.7M
Sector median$64.2M

Raised more than 98% of sector peers (real $). Modeled value above 78% of peers (estimate).

Niche peers — same stage & era

A tighter cohort than the sector chart above — only companies at the same stage (Series D+) that last raised in the same ~3-year era, ranked by modeled value est. (not money raised). This is the exact set the analyst read compares against, so a like-for-like cohort is what makes "over/under-valued" meaningful. This company ranks #27 of 33.

This companyCohort peer
$100.0M$1.0B$10.0B$100.0M$1.0BCapital raised (log)Kriya Therapeutics, Inc. · Series D+ Raised $870.3M · modeled $2.5B (est)Pathos AI, Inc. · Series D+ Raised $365.0M · modeled $2.4B (est)Sensei Biotherapeutics, Inc. · Series D+ Raised $348.9M · modeled $2.2B (est)Odyssey Therapeutics, Inc. · Series D+ Raised $590.9M · modeled $1.7B (est)Rhodenergy An Environmental Co Corp · Series D+ Raised $250.0M · modeled $1.7B (est)Tectonic Therapeutic, Inc. · Series D+ Raised $333.1M · modeled $1.7B (est)Lumicell, Inc. · Series D+ Raised $331.1M · modeled $1.7B (est)MapLight Therapeutics, Inc. · Series D+ Raised $356.2M · modeled $1.5B (est)SAB Biotherapeutics, Inc. · Series D+ Raised $182.5M · modeled $1.4B (est)Immunic, Inc. · Series D+ Raised $514.4M · modeled $1.3B (est)Predictive Oncology Inc. · Series D+ Raised $280.1M · modeled $1.3B (est)Vascular Perfusion Solutions, Inc. · Series D+ Raised $154.9M · modeled $1.2B (est)Avenzo Therapeutics, Inc. (this company) Raised $270.6M · modeled $355.7M (est)Avenzo Therapeutics, Inc.
CompanyStageRaised · realValue · estvs peer med.
Kriya Therapeutics, Inc.Series D+$870.3M$2.5B2.79×
Pathos AI, Inc.Series D+$365.0M$2.4B2.70×
Sensei Biotherapeutics, Inc.Series D+$348.9M$2.2B2.53×
Odyssey Therapeutics, Inc.Series D+$590.9M$1.7B1.94×
Rhodenergy An Environmental Co CorpSeries D+$250.0M$1.7B1.89×
Tectonic Therapeutic, Inc.Series D+$333.1M$1.7B1.89×
Lumicell, Inc.Series D+$331.1M$1.7B1.89×
MapLight Therapeutics, Inc.Series D+$356.2M$1.5B1.65×
SAB Biotherapeutics, Inc.Series D+$182.5M$1.4B1.53×
Immunic, Inc.Series D+$514.4M$1.3B1.45×
Predictive Oncology Inc.Series D+$280.1M$1.3B1.42×
Vascular Perfusion Solutions, Inc.Series D+$154.9M$1.2B1.37×
Avenzo Therapeutics, Inc. this companySeries D+$270.6M$355.7M0.40×
Full financing history

Stage is inferred from round size est., not reported on the filing — a round's dollar size maps to a bucket: Pre-Seed <$1.0M · Seed $1.0M–$4.0M · Series A $4.0M–$15M · Series B $15M–$40M · Series C $40M–$100M · Series D+ $100M–$400M · Growth/Late >$400M.

StageAmount · realAnnouncedPost-money · estValue · estConf.
Series B$31.5M2022-09-14$175.0M$485.8M90%
Series D+$385.9M2022-09-14$3.2B$7.7B90%
Series D+$223.4M2022-09-14$1.9B$4.4B90%
Series D+$47.2M2025-08-22$393.6M$355.7M90%
What happened at each round

Step-up, pace versus the sector's normal cadence, and revenue/exemption moves — read straight from the reported round facts reported.

  1. Series B$31.5M2022-09-14
    • First recorded raise — entered as Series B.
    • 6 investors on this round.
  2. Series D+$385.9M2022-09-14
    • Filed alongside the prior round (same month) — likely a tranche or amendment.
    • Round 12.2× larger than the prior — scaling up.
    • 22 investors on this round.
  3. Series D+$223.4M2022-09-14
    • Filed alongside the prior round (same month) — likely a tranche or amendment.
    • Round 1.7× smaller than the prior — bridge or down round.
    • 19 investors on this round.
  4. Series D+$47.2M2025-08-22
    • Raised again after 35 mo — slower than the ~14 mo sector norm.
    • Round 4.7× smaller than the prior — bridge or down round.
    • 20 investors on this round.
Intelligence
2026 ~Q3
Modeled next raise · ~12mo cadence
$47.2M
Modeled next size est.range $47.2M$75.6M
0.2×
Last step-up
$92.1M/yr
Capital velocity

Predictive signals are modeled est. from this company's own cadence and step-up, plus sector benchmarks — directional, not advice. Peer set and a CSV export live in your analyst workspace.

Key people & operators

Officers, directors and promoters named in this company's public recordsreported — the people who run it (not its investors). "Also runs" counts come from name-matching across all records, so verify before acting.

PersonRoleAlso runsTied since
Carl Gordon23 other2022-09
Judith Li7 other2022-09
Simeon George7 other2022-09
Garry Nicholson2 other2022-09
Michael Rome2 other2022-09
Patrick Machado2 other2025-08
Athena Countouriotis1 other2022-09
Mohammad Hirmand1 other2022-09
Brian Sun2022-09
Jakob Dupont, M.D., M.A.2022-09
Paolo Tombesi2022-09
Scott Lipman2022-09
Registry & provenance

Avenzo Therapeutics, Inc. is an official record sourced from the U.S. Securities and Exchange Commission (SEC). U.S. data is aggregated from SEC Form D filings.

United States
Country of record
US
Jurisdiction
1947742
SEC CIK
2022
Incorporated
Similar companies

Nearest neighbours across the whole database — matched on sector, stage and capital scale, and on shared operators (officers or directors named at both companies in public filings). A discovery shortlist, not a valuation cohort — verify before acting, the same way modeled figures are directional.

CompanySectorStageRaised · realValue · estWhy similar
ADARx Pharmaceuticals, Inc.PharmaceuticalsSeries D+$352.5M$2.8Bnetwork3 shared operators · same stage
ArriVent Biopharma, Inc.BiotechnologySeries D+$260.0M$2.0Bnetwork1 shared operator · same sector · same stage
Alumis Inc.BiotechnologySeries D+$240.0M$433.1Mnetwork1 shared operator · same sector · same stage
Tmunity Therapeutics, Inc.BiotechnologySeries C$175.0M$3.1Bnetwork2 shared operators · same sector
Adverum Biotechnologies, Inc.BiotechnologySeries D+$198.6M$1.6Bnetwork1 shared operator · same sector · same stage
Selecta Biosciences IncBiotechnologySeries D+$445.6M$1.4Bnetwork1 shared operator · same sector · same stage
Aadi Bioscience, Inc.BiotechnologySeries D+$451.8M$879.2Mnetwork1 shared operator · same sector · same stage
Compass Therapeutics LLCBiotechnologySeries D+$132.6M$900.7Mnetwork1 shared operator · same sector · same stage
Semantically similar

Matched by meaning, not labels — a local language model reads each company's name, sector and description and ranks the closest in that learned space. This catches look-alikes that cross sector boundaries; the structured list above explains its matches, this one trusts the text. Directional, like every modeled signal here.

CompanySectorStageValue · estMatch
Avenzoar Pharmaceuticals, Inc.BiotechnologyPre-Seed$8.2M95%
Aveta Biomics, Inc.BiotechnologySeries A$24.4M86%
Angarus Therapeutics, Inc.BiotechnologySeries A$328.8M82%
Acer Therapeutics Inc.BiotechnologySeries B$21.2M82%
Pharmesol Inc.BiotechnologySeed$4.2M82%
Endlyz Therapeutics, Inc.BiotechnologySeed$81.2M82%
Lapix Therapeutics Inc.BiotechnologySeries A$6.9M81%
Bectas Therapeutics, Inc.BiotechnologySeries A$66.0M81%
Frequently asked
How much funding has Avenzo Therapeutics, Inc. raised?
Avenzo Therapeutics, Inc. has raised approximately $270.6M in disclosed capital across 2 recorded financing rounds, aggregated from public filings.
What is Avenzo Therapeutics, Inc.'s estimated valuation?
Provath's modeled valuation for Avenzo Therapeutics, Inc. is approximately $355.7M (modeled range $214.1M–$433.8M). This is an algorithmic estimate derived from round sizes and same-niche peers — not a quoted or reported figure.
What funding stage is Avenzo Therapeutics, Inc. at?
Avenzo Therapeutics, Inc.'s latest modeled financing stage is Series D+. Its most recent recorded round closed around Fri Aug 22.
What does Avenzo Therapeutics, Inc. do and where is it based?
Avenzo Therapeutics, Inc. operates in the Biotechnology sector, based in SAN DIEGO.
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