Diligence memo · auto-generated · as of July 2, 2026

Aptinyx Inc.

Aptinyx Inc. looks fair against its niche peers and is dormant on financing cadence.

DeprioritizeFinancing has gone silent well past the sector's normal cadence — treat as inactive until outside confirmation of a live operation.

Businessfiled

Aptinyx Inc. operates in Pharmaceuticals, based in EVANSTON.

No verified homepage on file yet — operating evidence is limited to the public record.

Capital & rounds (filed)filed

Aptinyx Inc. has raised $95M in disclosed capital across 2 recorded rounds, aggregated from public filings. Its latest round is modeled as Series C (a $40M–$100M round).

Largest single filing: $70M on 2017-12-15.

Most recent recorded round closed around 2017-12-15.

Valuation (modeled)modeled

Provath models Aptinyx Inc. at approximately $2.5B (range $227M–$6.5B). This is an algorithmic estimate from round sizes and same-niche peers — not a quoted or reported figure.

Read: Fair. Modeled value is 1.06× the median modeled value of Series C Pharmaceuticals companies in 2016–2018 (32 peers) — value vs value, same stage and era. Within the normal band (106% of peer median) for its niche.

Financing rhythm & timingmixed

Historic cadence: a new round about every 19 months.

Last raise 8.5 yr ago; this sector typically re-raises about every 13 months.

Silent for over 3× the sector's normal cadence.

The last round stepped up 2.8× from the prior — scaling.

Comparablesmixed

Capital scale ranks ahead of 90% of Pharmaceuticals peers (1613 compared).

Modeled value ranks above 96% of those peers.

Closest niche peers: Amplyx Pharmaceuticals, Inc., Ligand Pharmaceuticals Inc, Homology Medicines, Inc., KSQ Therapeutics, Inc., TP Therapeutics, Inc..

Peoplefiled

14 named people on file across officers, directors and signatories.

Risks & flagsmixed

Financing has been silent well beyond sector cadence — possibly defunct, acquired, or paused.

No clearly named CEO/founder/principal in the surfaced records — key-person evidence is thin.