Companies · Biotechnology

Alphina Therapeutics, Inc.

New Haven · Biotechnology

Diligence memoA one-page analyst read on Alphina Therapeutics, Inc. — recommendation, valuation, rhythm, risks.
$17.0M
Total raised · real
2
Rounds
0.0×
Latest step-up
Top 36%
Sector rank · raised
Series B
Latest stage · inferred · Mon Feb 23 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

Alphina Therapeutics, Inc. looks under-valued against its niche peers and is active on financing cadence.

Synthesized from the figures below est. — every claim rests on a number shown on this page. Valuation uses the biotech sector profile.

Analyst read est. — computed against this company's niche peers in the same era. Inputs shown; not a quoted figure.

Under-valued
  • Modeled value is 0.01× the median modeled value of Series B Biotechnology companies in 2025–2027 (94 peers) — value vs value, same stage and era.
Active
  • Last raise 4 mo ago; this sector typically re-raises about every 14 months.
  • Raising on or ahead of the sector's normal rhythm.
Leadership

No named principal in this company's public records yet — see all operators below.

Explore how these operators interlock with other companies in the operator network.

Where it sits in Biotechnology

Alphina Therapeutics, Inc. is one of 4293 Biotechnology companies tracked from New Haven. By capital raised it ranks mid-pack (ahead of 65% of sector peers), and in the long tail by modeled valuation est..

Ranking is computed against this company's own sector cohort — reported capital is fact; valuation tiers are modeled.

pharma

As reported in public records reported — not modeled.

US
Jurisdiction
Rule 506(b)
Reg D exemption
3
Investors (latest)
2026-02-23
First sale
Amount raised vs valuation, by round

Solid bars are reported offering amounts reported; hatched bars are the modeled post-money valuation est. — both on one shared scale so you can read raise-vs-worth at each round directly. Use the toggles to overlay data labels and the niche-peer / market average value lines.

Amount raised · realModeled valuation · estCumulative funded · real
$0$125M$250M$375M$500MSeries B · 2021-09-07 Raised $17M (real) Modeled valuation $402M (est)$17M$402MSeries B2021Series B · 2026-02-23 Raised $154K (real) Modeled valuation $541K (est)$154K$541KSeries B2026+$154KCumulative $17M

The line shows cumulative reported funding over the period; + labels show new capital added between points when there is room. Toggle on-bar figures, plus the niche-peer and market averages, to read this company against its cohort. Benchmarks are modeled medians.

Financing ladder & sequence gaps
Series B$16.9M · 2021
Series B extension$154K · 2026

Stages are modeled from round size (public records carry no series label). No record for: Pre-Seed, Seed, Series A — the company may have raised it under a different exemption, merged it into an adjacent record, or skipped it. Sequence completeness: 25%.

Modeled valuation trajectory
$541K
Base estimate est.
$307K
Conservative case
$706K
Upside case
$854K
Modeled post-money

Round size and date are reported; the stage label is inferred from round size (latest is Series Ba $15M–$40M round). Valuation is modeled from stage benchmarks scaled by the biotech sector profile. Directional, not a quoted figure.

Series B · modeled $402.4M · 2021-09-072021Series B · modeled $541K · 2026-02-232026
Model inputs · modeled:benchmark-stage-stepup-v1
18%
Dilution assumption
Implied ownership sold in the financing.
54%
Survival probability
36% low · 66% high
1.54×/yr
Annual markup
1.86×/yr upside case
0.3 yr
Elapsed time used
0.3 yr actual, capped for stale marks
biotech
Sector profile
Adjusts growth and survival by industry.
Financing rhythm
54 mo
Avg between rounds
$3.8M/yr
Capital velocity
4.8 yr
On record since
2021
First round
2
Rounds on file
How it compares to the market

Benchmarked against 4293 companies in Biotechnology. Each bar is a median (the middle company, not an average — outliers don't skew it). Two yardsticks: real money raised (reported on Form D) and modeled value (our estimate est.). These are whole-sector medians across all stages, except the per-stage row.

Total raised — vs sector median (real $, all stages) 2.4× above median
This company$17.0M
Sector median$7.2M
Latest round — vs other Series B rounds in sector (real $, this stage) 0.0× of median
This company$154K
Sector median$17.5M
Modeled value — vs sector median (estimate, all stages) 0.0× of median
This company$541K
Sector median$64.2M

Raised more than 65% of sector peers (real $). Modeled value above 1% of peers (estimate).

Niche peers — same stage & era

A tighter cohort than the sector chart above — only companies at the same stage (Series B) that last raised in the same ~3-year era, ranked by modeled value est. (not money raised). This is the exact set the analyst read compares against, so a like-for-like cohort is what makes "over/under-valued" meaningful. This company ranks #94 of 94.

This companyCohort peer
$100K$1.0M$10.0M$100.0M$1.0B$10.0M$100.0M$1.0BCapital raised (log)MarvelBiome, Inc. · Series B Raised $54.9M · modeled $163.2M (est)Iantrek, Inc. · Series B Raised $58.2M · modeled $152.4M (est)Dualitas Therapeutics, Inc. · Series B Raised $32.6M · modeled $150.4M (est)Antares Therapeutics, Inc. · Series B Raised $70.0M · modeled $149.7M (est)OrthoBio Therapeutics, Inc. · Series B Raised $31.4M · modeled $147.5M (est)Medcura, Inc. · Series B Raised $40.9M · modeled $145.0M (est)Neurolutions Inc · Series B Raised $26.5M · modeled $144.9M (est)Renasant Bio, Inc. · Series B Raised $55.5M · modeled $144.0M (est)Caldera Therapeutics, Inc. · Series B Raised $37.5M · modeled $139.2M (est)VitriVax, Inc. · Series B Raised $29.4M · modeled $136.9M (est)DiaMedica Therapeutics Inc. · Series B Raised $110.4M · modeled $136.3M (est)OmniAb, Inc. · Series B Raised $30.0M · modeled $130.5M (est)Alphina Therapeutics, Inc. (this company) Raised $17.0M · modeled $541K (est)Alphina Therapeutics, Inc.
CompanyStageRaised · realValue · estvs peer med.
MarvelBiome, Inc.Series B$54.9M$163.2M2.11×
Iantrek, Inc.Series B$58.2M$152.4M1.97×
Dualitas Therapeutics, Inc.Series B$32.6M$150.4M1.94×
Antares Therapeutics, Inc.Series B$70.0M$149.7M1.93×
OrthoBio Therapeutics, Inc.Series B$31.4M$147.5M1.90×
Medcura, Inc.Series B$40.9M$145.0M1.87×
Neurolutions IncSeries B$26.5M$144.9M1.87×
Renasant Bio, Inc.Series B$55.5M$144.0M1.86×
Caldera Therapeutics, Inc.Series B$37.5M$139.2M1.80×
VitriVax, Inc.Series B$29.4M$136.9M1.77×
DiaMedica Therapeutics Inc.Series B$110.4M$136.3M1.76×
OmniAb, Inc.Series B$30.0M$130.5M1.68×
Alphina Therapeutics, Inc. this companySeries B$17.0M$541K0.01×
Full financing history

Stage is inferred from round size est., not reported on the filing — a round's dollar size maps to a bucket: Pre-Seed <$1.0M · Seed $1.0M–$4.0M · Series A $4.0M–$15M · Series B $15M–$40M · Series C $40M–$100M · Series D+ $100M–$400M · Growth/Late >$400M.

StageAmount · realAnnouncedPost-money · estValue · estConf.
Series B$16.9M2021-09-07$93.6M$402.4M90%
Series B$154K2026-02-23$854K$541K90%
What happened at each round

Step-up, pace versus the sector's normal cadence, and revenue/exemption moves — read straight from the reported round facts reported.

  1. Series B$16.9M2021-09-07
    • First recorded raise — entered as Series B.
    • 19 investors on this round.
  2. Series B$154K2026-02-23
    • Raised again after 54 mo — slower than the ~14 mo sector norm.
    • Round 109.6× smaller than the prior — bridge or down round.
    • 3 investors on this round.
Intelligence
2030 ~Q3
Modeled next raise · ~54mo cadence
$154K
Modeled next size est.range $154K$246K
0.0×
Last step-up
$3.8M/yr
Capital velocity

Predictive signals are modeled est. from this company's own cadence and step-up, plus sector benchmarks — directional, not advice. Peer set and a CSV export live in your analyst workspace.

Key people & operators

Officers, directors and promoters named in this company's public recordsreported — the people who run it (not its investors). "Also runs" counts come from name-matching across all records, so verify before acting.

PersonRoleAlso runsTied since
Kevin L. Rakin6 other2021-09
Ranjit L. Bindra2 other2021-09
Anurag L. Agarwal2021-09
Barbara J Fox2026-02
Colleen J Cuffaro2026-02
Colleen L. Cuffaro2021-09
Kevin J Rakin2026-02
Matthew J Cohen2026-02
Nicholas J Galli2026-02
Ranjit J Bindra2026-02
Stanley L. Choy2021-09
Registry & provenance

Alphina Therapeutics, Inc. is an official record sourced from the U.S. Securities and Exchange Commission (SEC). U.S. data is aggregated from SEC Form D filings.

United States
Country of record
US
Jurisdiction
1882991
SEC CIK
Similar companies

Nearest neighbours across the whole database — matched on sector, stage and capital scale, and on shared operators (officers or directors named at both companies in public filings). A discovery shortlist, not a valuation cohort — verify before acting, the same way modeled figures are directional.

CompanySectorStageRaised · realValue · estWhy similar
Modifi Biosciences, Inc.BiotechnologySeries A$11.5M$4.9Mnetwork2 shared operators · same sector
CapeHaven Holding Company, LLCBiotechnologySeed$1.4M$3.9Mnetwork2 shared operators · same sector
Smart Health Diagnostics CoBiotechnologySeries B$17.3M$1.8Msame sector · same stage
CyVek, Inc.BiotechnologySeries A$22.3M$361.5Mnetwork1 shared operator · same sector
Intrommune Therapeutics, Inc.BiotechnologySeries B$25.5M$1.9Msame sector · same stage
Allarity Therapeutics, Inc.BiotechnologySeries B$26.9M$3.5Msame sector · same stage
KIYATEC Inc.BiotechnologySeries B$32.3M$1.6Msame sector · same stage
Mateon Therapeutics IncBiotechnologySeries B$45.3M$1.1Msame sector · same stage
Semantically similar

Matched by meaning, not labels — a local language model reads each company's name, sector and description and ranks the closest in that learned space. This catches look-alikes that cross sector boundaries; the structured list above explains its matches, this one trusts the text. Directional, like every modeled signal here.

CompanySectorStageValue · estMatch
Aloe Therapeutics Inc.BiotechnologyPre-Seed$565K87%
Alcresta Therapeutics, Inc.BiotechnologySeries C$409.6M87%
Aldebaran Therapeutics, Inc.BiotechnologyPre-Seed$16.3M85%
Aldeyra Therapeutics, Inc.BiotechnologySeries A$361.5M85%
Opprtna Therapeutics, Inc.BiotechnologyPre-Seed$633K84%
Aloft Biotechnologies, Inc.BiotechnologyPre-Seed$399K83%
Aardvark Therapeutics, Inc.BiotechnologySeries C$808.1M83%
Halia Therapeutics, Inc.BiotechnologySeries A$1.1M83%
Frequently asked
How much funding has Alphina Therapeutics, Inc. raised?
Alphina Therapeutics, Inc. has raised approximately $17.0M in disclosed capital across 2 recorded financing rounds, aggregated from public filings.
What is Alphina Therapeutics, Inc.'s estimated valuation?
Provath's modeled valuation for Alphina Therapeutics, Inc. is approximately $541K (modeled range $307K–$706K). This is an algorithmic estimate derived from round sizes and same-niche peers — not a quoted or reported figure.
What funding stage is Alphina Therapeutics, Inc. at?
Alphina Therapeutics, Inc.'s latest modeled financing stage is Series B. Its most recent recorded round closed around Mon Feb 23.
What does Alphina Therapeutics, Inc. do and where is it based?
Alphina Therapeutics, Inc. operates in the Biotechnology sector, based in New Haven.
Explore related

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