Companies · Pharmaceuticals

Actuate Therapeutics, Inc.

FORT WORTH · Pharmaceuticals

Diligence memoA one-page analyst read on Actuate Therapeutics, Inc. — recommendation, valuation, rhythm, risks.
$127.5M
Total raised · real
11
Rounds
0.1×
Latest step-up
Top 8%
Sector rank · raised
Series C
Latest stage · inferred · Fri Jun 27 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

Actuate Therapeutics, Inc. looks under-valued against its niche peers and is active on financing cadence.

Synthesized from the figures below est. — every claim rests on a number shown on this page. Valuation uses the pharma sector profile.

Analyst read est. — computed against this company's niche peers in the same era. Inputs shown; not a quoted figure.

Under-valued
  • Modeled value is 0.19× the median modeled value of Series C Pharmaceuticals companies in 2025–2027 (26 peers) — value vs value, same stage and era.
Active
  • Last raise 12 mo ago; this sector typically re-raises about every 13 months.
  • Raising on or ahead of the sector's normal rhythm.
Leadership

No named principal in this company's public records yet — see all operators below.

Explore how these operators interlock with other companies in the operator network.

Where it sits in Pharmaceuticals

Actuate Therapeutics, Inc. is one of 1613 Pharmaceuticals companies tracked from FORT WORTH. By capital raised it ranks among the largest (ahead of 93% of sector peers), and in the long tail by modeled valuation est..

Ranking is computed against this company's own sector cohort — reported capital is fact; valuation tiers are modeled.

pharma

As reported in public records reported — not modeled.

US
Jurisdiction
Rule 506(b)
Reg D exemption
8
Investors (latest)
2025-06-27
First sale
Amount raised vs valuation, by round

Solid bars are reported offering amounts reported; hatched bars are the modeled post-money valuation est. — both on one shared scale so you can read raise-vs-worth at each round directly. Use the toggles to overlay data labels and the niche-peer / market average value lines.

Amount raised · realModeled valuation · estCumulative funded · real
$0$250M$500M$750M$1.0BPre-Seed · 2015-09-29 Raised $410K (real) Modeled valuation $19M (est)Pre-Seed2015Pre-Seed · 2017-01-18 Raised $150K (real) Modeled valuation $7.1M (est)Pre-Seed2017Seed · 2017-03-17 Raised $3.0M (real) Modeled valuation $114M (est)Seed2017Series A · 2018-08-28 Raised $4.0M (real) Modeled valuation $125M (est)Series A2018Series B · 2019-04-30 Raised $22M (real) Modeled valuation $744M (est)Series B2019Series B · 2019-10-01 Raised $6.5M (real) Modeled valuation $221M (est)Series B2019Seed · 2019-10-01 Raised $3.9M (real) Modeled valuation $150M (est)Seed2019Series B · 2020-11-30 Raised $14M (real) Modeled valuation $418M (est)Series B2020Series B · 2022-09-30 Raised $19M (real) Modeled valuation $271M (est)Series B2022Series A · 2022-09-30 Raised $11M (real) Modeled valuation $126M (est)Series A2022Series B · 2024-02-20 Raised $3.0M (real) Modeled valuation $24M (est)Series B2024Series C · 2025-04-10 Raised $50M (real) Modeled valuation $334M (est)Series C2025Series C · 2025-06-27 Raised $4.7M (real) Modeled valuation $29M (est)Series C2025Cumulative $143M

The line shows cumulative reported funding over the period; + labels show new capital added between points when there is room. Toggle on-bar figures, plus the niche-peer and market averages, to read this company against its cohort. Benchmarks are modeled medians.

Financing ladder & sequence gaps
Pre-Seed$410K · 2015
Pre-Seed extension$150K · 2017
Seed$3.0M · 2017
Series A$4.0M · 2018
Series B$21.9M · 2019
Series B extension$6.5M · 2019
Bridge · Series B-stage$3.9M · 2019smaller follow-on
Series B extension$14.5M · 2020
Series B extension$19.3M · 2022
Bridge · Series B-stage$11.2M · 2022smaller follow-on
Series B extension$3.0M · 2024
Series C$50.0M · 2025
Series C extension$4.7M · 2025

Stages are modeled from round size (public records carry no series label). Ladder is contiguous — every modeled rung has a record.

Modeled valuation trajectory
$29.0M
Base estimate est.
$15.2M
Conservative case
$38.4M
Upside case
$31.1M
Modeled post-money

Round size and date are reported; the stage label is inferred from round size (latest is Series Ca $40M–$100M round). Valuation is modeled from stage benchmarks scaled by the pharma sector profile. Directional, not a quoted figure.

Pre-Seed · modeled $19.4M · 2015-09-292015Pre-Seed · modeled $7.1M · 2017-01-18Seed · modeled $114.1M · 2017-03-17Series A · modeled $124.7M · 2018-08-28Series B · modeled $744.2M · 2019-04-30Series B · modeled $221.0M · 2019-10-01Seed · modeled $150.0M · 2019-10-01Series B · modeled $418.0M · 2020-11-30Series B · modeled $270.6M · 2022-09-30Series A · modeled $126.3M · 2022-09-30Series B · modeled $24.2M · 2024-02-20Series C · modeled $334.4M · 2025-04-10Series C · modeled $29.0M · 2025-06-272025
Model inputs · modeled:benchmark-stage-stepup-v1
15%
Dilution assumption
Implied ownership sold in the financing.
66%
Survival probability
49% low · 76% high
1.42×/yr
Annual markup
1.62×/yr upside case
1.0 yr
Elapsed time used
1.0 yr actual, capped for stale marks
pharma
Sector profile
Adjusts growth and survival by industry.
Financing rhythm
10 mo
Avg between rounds
$13.1M/yr
Capital velocity
10.8 yr
On record since
2015
First round
13
Rounds on file
How it compares to the market

Benchmarked against 1613 companies in Pharmaceuticals. Each bar is a median (the middle company, not an average — outliers don't skew it). Two yardsticks: real money raised (reported on Form D) and modeled value (our estimate est.). These are whole-sector medians across all stages, except the per-stage row.

Total raised — vs sector median (real $, all stages) 16× above median
This company$127.5M
Sector median$8.1M
Latest round — vs other Series C rounds in sector (real $, this stage) 0.1× of median
This company$4.7M
Sector median$46.4M
Modeled value — vs sector median (estimate, all stages) 0.4× of median
This company$29.0M
Sector median$76.1M

Raised more than 93% of sector peers (real $). Modeled value above 33% of peers (estimate).

Niche peers — same stage & era

A tighter cohort than the sector chart above — only companies at the same stage (Series C) that last raised in the same ~3-year era, ranked by modeled value est. (not money raised). This is the exact set the analyst read compares against, so a like-for-like cohort is what makes "over/under-valued" meaningful. This company ranks #23 of 26.

This companyCohort peer
$10.0M$100.0M$1.0B$10.0M$100.0M$1.0BCapital raised (log)BlossomHill Therapeutics, Inc. · Series C Raised $245.8M · modeled $452.7M (est)Rivus Pharmaceuticals, Inc. · Series C Raised $223.5M · modeled $416.3M (est)Sparrow Pharmaceuticals, Inc. · Series C Raised $73.3M · modeled $386.6M (est)Arthrosi Therapeutics, Inc. · Series C Raised $132.9M · modeled $385.6M (est)Altesa BioSciences, Inc. · Series C Raised $110.0M · modeled $373.9M (est)Mirum Pharmaceuticals, Inc. · Series C Raised $138.5M · modeled $348.3M (est)Eyenovia, Inc. · Series C Raised $66.0M · modeled $312.6M (est)Alveus Therapeutics, Inc. · Series C Raised $56.9M · modeled $298.1M (est)Aeovian Pharmaceuticals, Inc. · Series C Raised $125.0M · modeled $297.8M (est)Curevo, Inc. · Series C Raised $110.0M · modeled $293.2M (est)Neuropathix, Inc. · Series C Raised $51.3M · modeled $271.0M (est)Verrica Pharmaceuticals Inc. · Series C Raised $77.5M · modeled $269.0M (est)Actuate Therapeutics, Inc. (this company) Raised $127.5M · modeled $29.0M (est)Actuate Therapeutics, Inc.
CompanyStageRaised · realValue · estvs peer med.
BlossomHill Therapeutics, Inc.Series C$245.8M$452.7M3.02×
Rivus Pharmaceuticals, Inc.Series C$223.5M$416.3M2.78×
Sparrow Pharmaceuticals, Inc.Series C$73.3M$386.6M2.58×
Arthrosi Therapeutics, Inc.Series C$132.9M$385.6M2.57×
Altesa BioSciences, Inc.Series C$110.0M$373.9M2.49×
Mirum Pharmaceuticals, Inc.Series C$138.5M$348.3M2.32×
Eyenovia, Inc.Series C$66.0M$312.6M2.08×
Alveus Therapeutics, Inc.Series C$56.9M$298.1M1.99×
Aeovian Pharmaceuticals, Inc.Series C$125.0M$297.8M1.99×
Curevo, Inc.Series C$110.0M$293.2M1.96×
Neuropathix, Inc.Series C$51.3M$271.0M1.81×
Verrica Pharmaceuticals Inc.Series C$77.5M$269.0M1.79×
Actuate Therapeutics, Inc. this companySeries C$127.5M$29.0M0.19×
Full financing history

Stage is inferred from round size est., not reported on the filing — a round's dollar size maps to a bucket: Pre-Seed <$1.0M · Seed $1.0M–$4.0M · Series A $4.0M–$15M · Series B $15M–$40M · Series C $40M–$100M · Series D+ $100M–$400M · Growth/Late >$400M.

StageAmount · realAnnouncedPost-money · estValue · estConf.
Pre-Seed$410K2015-09-29$2.3M$19.4M85%
Pre-Seed$150K2017-01-18$833K$7.1M90%
Seed$3.0M2017-03-17$15.0M$114.1M90%
Series A$4.0M2018-08-28$18.3M$124.7M90%
Series B$21.9M2019-04-30$121.6M$744.2M90%
Series B$6.5M2019-10-01$36.1M$221.0M90%
Seed$3.9M2019-10-01$19.7M$150.0M90%
Series B$14.5M2020-11-30$80.5M$418.0M90%
Series B$19.3M2022-09-30$107.4M$270.6M90%
Series A$11.2M2022-09-30$50.8M$126.3M90%
Series B$3.0M2024-02-20$16.7M$24.2M90%
Series C$50.0M2025-04-10$333.3M$334.4M90%
Series C$4.7M2025-06-27$31.1M$29.0M90%
What happened at each round

Step-up, pace versus the sector's normal cadence, and revenue/exemption moves — read straight from the reported round facts reported.

  1. Pre-Seed$410K2015-09-29
    • First recorded raise — entered as Pre-Seed.
    • 4 investors on this round.
  2. Pre-Seed$150K2017-01-18
    • Raised 16 mo later, in step with the ~13 mo sector norm.
    • Round 2.7× smaller than the prior — bridge or down round.
    • 1 investor on this round.
  3. Seed$3.0M2017-03-17
    • Came back fast: 2 mo vs the ~13 mo sector norm.
    • Round 20.0× larger than the prior — scaling up.
    • 2 investors on this round.
  4. Series A$4.0M2018-08-28
    • Raised 17 mo later, in step with the ~13 mo sector norm.
    • Round 1.3× larger than the prior — scaling up.
    • 18 investors on this round.
  5. Series B$21.9M2019-04-30
    • Raised 8 mo later, in step with the ~13 mo sector norm.
    • Round 5.4× larger than the prior — scaling up.
    • 21 investors on this round.
  6. Series B$6.5M2019-10-01
    • Came back fast: 5 mo vs the ~13 mo sector norm.
    • Round 3.4× smaller than the prior — bridge or down round.
    • 17 investors on this round.
  7. Seed$3.9M2019-10-01
    • Filed alongside the prior round (same month) — likely a tranche or amendment.
    • Round 1.6× smaller than the prior — bridge or down round.
    • 14 investors on this round.
  8. Series B$14.5M2020-11-30
    • Raised 14 mo later, in step with the ~13 mo sector norm.
    • Round 3.7× larger than the prior — scaling up.
    • 14 investors on this round.
  9. Series B$19.3M2022-09-30
    • Raised again after 22 mo — slower than the ~13 mo sector norm.
    • Round 1.3× larger than the prior — scaling up.
    • 95 investors on this round.
  10. Series A$11.2M2022-09-30
    • Filed alongside the prior round (same month) — likely a tranche or amendment.
    • Round 1.7× smaller than the prior — bridge or down round.
    • 30 investors on this round.
  11. Series B$3.0M2024-02-20
    • Raised 17 mo later, in step with the ~13 mo sector norm.
    • Round 3.7× smaller than the prior — bridge or down round.
    • 1 investor on this round.
  12. Series C$50.0M2025-04-10
    • Raised 14 mo later, in step with the ~13 mo sector norm.
    • Round 16.7× larger than the prior — scaling up.
    • 1 investor on this round.
  13. Series C$4.7M2025-06-27
    • Came back fast: 3 mo vs the ~13 mo sector norm.
    • Round 10.7× smaller than the prior — bridge or down round.
    • 8 investors on this round.
Intelligence
2026 ~Q2
Modeled next raise · ~10mo cadence
$4.7M
Modeled next size est.range $4.7M$7.5M
0.1×
Last step-up
$13.1M/yr
Capital velocity

Predictive signals are modeled est. from this company's own cadence and step-up, plus sector benchmarks — directional, not advice. Peer set and a CSV export live in your analyst workspace.

Key people & operators

Officers, directors and promoters named in this company's public recordsreported — the people who run it (not its investors). "Also runs" counts come from name-matching across all records, so verify before acting.

PersonRoleAlso runsTied since
Aaron Fletcher4 other2024-02
Todd Thomson3 other2024-02
Aaron G.L. Fletcher1 other2025-04
Daniel Schmitt1 other2020-11
Dan Zabrowski1 other2024-02
Leslie Wayne Kreis, Jr.1 other2015-09
Aaron Glenn Louis Fletcher2015-09
Alex Wayne Andrianopoulos2019-10
Amy G.L. Ronneberg2025-04
Andrew G.L. Mazar2025-04
Daniel G.L. Zabrowski2025-04
Daniel M. Schmitt2015-09
Dan Wayne Zabrowski2022-09
Jason G.L. Keyes2025-04
Leslie Kreis, Jr.2024-02
NEIL WAYNE BAJPAYEE2019-10
Pascal Wayne Krotee2020-11
Paul Lytle2025-04
Roger G.L. Sawhney2025-04
Todd G.L. Thomson2025-04
Todd Wayne Thomson2022-09
Registry & provenance

Actuate Therapeutics, Inc. is an official record sourced from the U.S. Securities and Exchange Commission (SEC). U.S. data is aggregated from SEC Form D filings.

United States
Country of record
US
Jurisdiction
1652935
SEC CIK
Similar companies

Nearest neighbours across the whole database — matched on sector, stage and capital scale, and on shared operators (officers or directors named at both companies in public filings). A discovery shortlist, not a valuation cohort — verify before acting, the same way modeled figures are directional.

CompanySectorStageRaised · realValue · estWhy similar
Diffusion Pharmaceuticals Inc.PharmaceuticalsSeries C$140.0M$26.3Msame sector · same stage
Galera Therapeutics, Inc.PharmaceuticalsSeries C$143.7M$21.2Msame sector · same stage
Lung Therapeutics, Inc.PharmaceuticalsSeries B$87.5M$174.9Mnetwork1 shared operator · same sector
ONL Therapeutics, Inc.BiotechnologySeries C$111.5M$496.0Mnetwork1 shared operator · same stage
Trxade Group, Inc.PharmaceuticalsSeries C$74.2M$10.4Msame sector · same stage
Gilgamesh Pharma Inc.PharmaceuticalsSeries C$72.7M$10.8Msame sector · same stage
BiomX Inc.PharmaceuticalsSeries C$72.3M$16.9Msame sector · same stage
Transposon Therapeutics, Inc.PharmaceuticalsSeries C$59.1M$40.6Msame sector · same stage
Semantically similar

Matched by meaning, not labels — a local language model reads each company's name, sector and description and ranks the closest in that learned space. This catches look-alikes that cross sector boundaries; the structured list above explains its matches, this one trusts the text. Directional, like every modeled signal here.

CompanySectorStageValue · estMatch
Arcuate Therapeutics, Inc.PharmaceuticalsSeries A$154.9M86%
Acta Pharmaceuticals, Inc.PharmaceuticalsSeries A$121.5M84%
Actimis Pharmaceuticals IncPharmaceuticalsPre-Seed$21.4M83%
Actym Therapeutics, Inc.BiotechnologySeries A$96.1M82%
Actuate Health Inc.HealthtechPre-Seed$10.3M82%
Avenue Therapeutics, Inc.PharmaceuticalsPre-Seed$2.5M78%
Actinobac Biomed, Inc.PharmaceuticalsSeed$38.0M77%
Chase Therapeutics CorpPharmaceuticalsSeed$152.2M77%
Frequently asked
How much funding has Actuate Therapeutics, Inc. raised?
Actuate Therapeutics, Inc. has raised approximately $127.5M in disclosed capital across 11 recorded financing rounds, aggregated from public filings.
What is Actuate Therapeutics, Inc.'s estimated valuation?
Provath's modeled valuation for Actuate Therapeutics, Inc. is approximately $29.0M (modeled range $15.2M–$38.4M). This is an algorithmic estimate derived from round sizes and same-niche peers — not a quoted or reported figure.
What funding stage is Actuate Therapeutics, Inc. at?
Actuate Therapeutics, Inc.'s latest modeled financing stage is Series C. Its most recent recorded round closed around Fri Jun 27.
What does Actuate Therapeutics, Inc. do and where is it based?
Actuate Therapeutics, Inc. operates in the Pharmaceuticals sector, based in FORT WORTH.
Explore related

See where Actuate Therapeutics, Inc. sits in the wider market — its sector, location and stage cohorts, each with their own leaderboards and capital-flow timelines.

Is this your company?

If you work at Actuate Therapeutics, Inc., claim this profile or suggest a correction. We aggregate from public filings, so help us keep your description, website and links accurate.

Is this your company? Update your profile or add contact details — and choose exactly who can reach you. Reviewed before anything is published.